Improving lipid porduction by strain develponet of microagae: strateges, challenges and perspectives
- Title
- Improving lipid porduction by strain develponet of microagae: strateges, challenges and perspectives
- Author
- 진언선
- Keywords
- Microalgae; Strain development; Genome editing; Lipid productivity
- Issue Date
- 2019-11
- Publisher
- ELSEVIER SCI LTD
- Citation
- BIORESOURCE TECHNOLOGY, v. 292, article no. 121953
- Abstract
- Over the past decade, the number of original articles and reviews presenting microalgae as a promising feedstock for biodiesel has increased tremendously. Many improvements of microalgae have been achieved through selection and strain development for industrial applications. However, the large-scale production of lipids for commercialization is not yet realistic because the production is still much more expensive than that of agricultural products. This review summarizes recent research on the induction of lipid biosynthesis in microalgae and the various strategies of genetic and metabolic engineering for enhancing lipid production. Strain engineering targets are proposed based on these strategies. To address current limitations of strain engineering for lipid production, this review provides insights on recent engineering strategies based on molecular tools and methods, and also discusses further perspectives.
- URI
- https://www.sciencedirect.com/science/article/pii/S0960852419311836?via%3Dihubhttps://repository.hanyang.ac.kr/handle/20.500.11754/155550
- ISSN
- 0960-8524; 1873-2976
- DOI
- 10.1016/j.biortech.2019.121953
- Appears in Collections:
- COLLEGE OF NATURAL SCIENCES[S](자연과학대학) > LIFE SCIENCE(생명과학과) > Articles
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