The intelligent data management system for Toxicogenomics
- Title
- The intelligent data management system for Toxicogenomics
- Author
- 황승용
- Keywords
- cDNA microarray; data management; toxicogenomics
- Issue Date
- 2004-11
- Publisher
- JAPAN SOC VET SCI
- Citation
- JOURNAL OF VETERINARY MEDICAL SCIENCE, v.66, Issue.11, Page.1335-1338
- Abstract
- Toxicogenomics is now emerging as one of the most important genomic application because the toxicity test based on gene expression profiles is expected to be more precise and efficient than current histopathological approaches in a pre-clinical phase. One of the challenging issues in toxicogenomics is the construction of intelligent database management system which can deal with heterogeneous and complex data from many different experimental and information sources. TEST(Toxicogenomics for Efficient Safety Test) database is especially focused on the connectivity of heterogeneous data and the intelligent query system which enable users to obtain relevant useful information from the complex data sets. The database deals with four kinds of information; compound, histopathology, gene expression, and annotation information. Currently, TEST database maintains toxicogenomics information for 16 compounds, 45 microarrays, 190 animal experiments, and customized 4.8 K rat clone set. Our presented system is expected to be a good information source for studying of toxicology mechanism in the genome-wide level and can also be applied to the designing toxicity test chip.
- URI
- https://www.jstage.jst.go.jp/article/jvms/66/11/66_11_1335/_articlehttps://repository.hanyang.ac.kr/handle/20.500.11754/154881
- ISSN
- 09167250
- Appears in Collections:
- COLLEGE OF SCIENCE AND CONVERGENCE TECHNOLOGY[E](과학기술융합대학) > MOLECULAR AND LIFE SCIENCE(분자생명과학과) > Articles
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