Applicability of X-ray microscopy to non-contact tablet mass estimation
- Title
- Applicability of X-ray microscopy to non-contact tablet mass estimation
- Author
- 김용균
- Keywords
- Mass measurement; Tablet manufacturing; X-ray transmittance; Imaging plate detector; Volume measurement
- Issue Date
- 2018-05
- Publisher
- SPRINGER
- Citation
- JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, v. 316, no. 3, page. 1033-1038
- Abstract
- The pharmaceutical tablet manufacturing process requires a tablet mass measuring step to ensure that all tablets have the prescribed dosage. The digital scales commonly used for that purpose require tens of seconds to stabilize, resulting in a substantial slow-down of the manufacturing process. The alternative visual approaches are fallible because of the potential existence of voids and cracks in the tablets. This paper uses an X-ray microscopy for mass measurement. Albeit with some constraints concerning tablet size and constituents, the approach can measure a tablet's mass in under one second, and may constitute, in the future, a viable and practical approach.
- URI
- https://link.springer.com/article/10.1007%2Fs10967-018-5867-4https://repository.hanyang.ac.kr/handle/20.500.11754/118708
- ISSN
- 0236-5731; 1588-2780
- DOI
- 10.1007/s10967-018-5867-4
- Appears in Collections:
- COLLEGE OF ENGINEERING[S](공과대학) > NUCLEAR ENGINEERING(원자력공학과) > Articles
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