Total Syntheses of Ningalins D and G
- Title
- Total Syntheses of Ningalins D and G
- Author
- 조천규
- Keywords
- FISCHER INDOLE SYNTHESIS; METHYL ARENES; ALKALOIDS; REARRANGEMENT; HYDRAZIDES; ACID; BROMINATION; LAMELLARINS; COMBINATION; IODINATION
- Issue Date
- 2017-08
- Publisher
- AMER CHEMICAL SOC
- Citation
- ORGANIC LETTERS, v. 19, no. 17, page. 4688-4691
- Abstract
- A flexible synthetic strategy for the total syntheses of ningalins D and G is described. The highly effective TMS-OTf/2,6-lutidine-mediated [3,3]-sigmatropic rearrangement of densely loaded dinaphthyl hydrazides and cyclization of the resulting 2,2'-diamino-1,1'-dinaphthyls afforded the key 7H-dibenzo[c,g]carbazole intermediates. Successful conversions to biphenylene quinone methides followed by regioselective brominations completed the total syntheses of the titled marine alkaloids.
- URI
- https://pubs.acs.org/doi/10.1021/acs.orglett.7b02372https://repository.hanyang.ac.kr/handle/20.500.11754/115155
- ISSN
- 1523-7060; 1523-7052
- DOI
- 10.1021/acs.orglett.7b02372
- Appears in Collections:
- COLLEGE OF NATURAL SCIENCES[S](자연과학대학) > CHEMISTRY(화학과) > Articles
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