Formation of Highly Aligned Collagen Nanofibers by Continuous Cyclic Stretch of a Collagen Hydrogel Sheet
- Title
- Formation of Highly Aligned Collagen Nanofibers by Continuous Cyclic Stretch of a Collagen Hydrogel Sheet
- Author
- 이원철
- Keywords
- collagen; continuous cyclic stretch; corneal stroma; highly aligned collagen nanofibers; smooth muscle cell; TISSUE ENGINEERING APPLICATIONS; HUMAN CORNEAL STROMA; SCAFFOLD; ALIGNMENT; CELLS; HEART; FIELD
- Issue Date
- 2016-07
- Publisher
- WILEY-V C H VERLAG GMBH
- Citation
- MACROMOLECULAR BIOSCIENCE, v. 16, No 7, Page. 995-1000
- Abstract
- A collagen sheet with highly aligned collagen fibers is fabricated by continuous cyclic stretch. The rearrangement of the collagen fibers depends on the different process parameters of the cyclic stretch, including magnitude, frequency, and period of stretch. The collagen fibers are aligned perpendicularly to the direction of the stretch. Corneal stromal cells and smooth muscle cells cultivated on the highly aligned collagen sheet show alignment along the collagen fibers without the stretch during culture. Thus, the sheet can be a suitable scaffold for use in regenerative medicine.
- URI
- https://onlinelibrary.wiley.com/doi/full/10.1002/mabi.201600068https://repository.hanyang.ac.kr/handle/20.500.11754/102606
- ISSN
- 1616-5187; 1616-5195
- DOI
- 10.1002/mabi.201600068
- Appears in Collections:
- COLLEGE OF ENGINEERING SCIENCES[E](공학대학) > MECHANICAL ENGINEERING(기계공학과) > Articles
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