Impact of the Surveillance Interval on the Survival of Patients Who Undergo Curative Surgery for Gastric Cancer
- Title
- Impact of the Surveillance Interval on the Survival of Patients Who Undergo Curative Surgery for Gastric Cancer
- Author
- 박찬혁
- Keywords
- LAPAROSCOPY-ASSISTED GASTRECTOMY; FOLLOW-UP; COLORECTAL-CANCER; ASYMPTOMATIC RECURRENCE; RETROSPECTIVE COHORT; RESECTION; METAANALYSIS
- Issue Date
- 2016-02
- Publisher
- SPRINGER
- Citation
- ANNALS OF SURGICAL ONCOLOGY, v. 23, NO 2, Page. 539-545
- Abstract
- For patients who undergo gastrectomy for gastric cancer, systematic follow-up evaluation to detect recurrent lesions is recommended, although the benefits of a surveillance program using short-term imaging studies have not been evaluated. This study reviewed the clinical data of patients who underwent curative surgery for gastric cancer using a prospective database. Patients with recurrence were classified according to surveillance interval as follows: a parts per thousand currency sign3, 3-6, and 6-12 months. Of the 2785 patients who underwent curative surgery for gastric cancer, 376 (13.5 %) had intraabdominal recurrences, excluding the stomach. Multivariable analysis showed that a short surveillance interval did not increase the post-recurrence survival duration (with 6-12 months as the reference: a parts per thousand currency sign3 months: hazard ratio [HR] 0.954; 95 % confidence interval [CI] 0.689-1.323; 3-6 months: HR 0.994, 95 % CI 0.743-1.330). In addition, short surveillance intervals did not increase overall survival (with 6-12 months as the reference: a parts per thousand currency sign3 months: HR 0.969; 95 % CI 0.699-1.342; 3-6 months: HR 0.955; 95 % CI 0.711-1.285). In contrast to the surveillance interval, age, cancer stage, symptoms at recurrence, and recurrence time after gastrectomy were factors associated with both post-recurrence survival and overall survival. Although the detection of recurrence before symptoms helped to prolong both post-recurrence survival and overall survival, shortening the surveillance interval to less than 6 months did not improve either the patient's post-recurrence survival or overall survival. Hence, it is not recommended that asymptomatic patients undergo surveillance involving imaging studies more often than once a year.
- URI
- https://link.springer.com/article/10.1245%2Fs10434-015-4866-8http://hdl.handle.net/20.500.11754/34152
- ISSN
- 1068-9265; 1534-4681
- DOI
- 10.1245/s10434-015-4866-8
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
- Files in This Item:
There are no files associated with this item.
- Export
- RIS (EndNote)
- XLS (Excel)
- XML