Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 임창환 | - |
dc.date.accessioned | 2018-05-28T06:00:42Z | - |
dc.date.available | 2018-05-28T06:00:42Z | - |
dc.date.issued | 2016-05 | - |
dc.identifier.citation | PSYCHIATRY INVESTIGATION, v. 13, NO 3, Page. 349-359 | en_US |
dc.identifier.issn | 1738-3684 | - |
dc.identifier.issn | 1976-3026 | - |
dc.identifier.uri | http://psychiatryinvestigation.org/journal/view.php?doi=10.4306/pi.2016.13.3.349 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/71565 | - |
dc.description.abstract | Objective Healthy individuals show stronger gamma-band activities (GBAs) for socially relevant stimuli (human faces) than for non-relevant ones. This study aimed to examine whether this gamma-band preference occurs in patients with schizophrenia. Methods EEG was recorded for 24 patients with schizophrenia and 23 healthy controls while they viewed pictures of human faces, chairs, and nature scenes. The spectral powers of high-beta (20-30 Hz) and gamma (30-80 Hz) frequencies were analyzed along 3 mid line cortical regions, and phase synchronization was calculated. Results Compared to the response to non-facial stimuli, higher event related deactivation to facial stimuli was observed for the high beta frequency across groups. For the gamma frequency, early-stage GBA was increased and late-stage GBA was decreased for all 3 stimuli in patients with schizophrenia compared to healthy controls. Preferential GBA patterns (100-200 and 200-300 ms) were found in healthy controls, but not in patients with schizophrenia. Significant correlation existed between negative symptoms and GBA in the frontal region for chair and scene stimuli. There was no significant intergroup difference in phase synchronization pattern. Conclusion Our results suggest that patients with schizophrenia have deficits in the preferential pattern of GBA for human faces and the deficits in the preferential pattern were mainly influenced by over-response to socially non-relevant stimuli. | en_US |
dc.description.sponsorship | The authors thank JI Kim and SH Jeon for their assistance. This work was supported by a grants from the Korea Science and Engineering Foundation (KOSEF), which is funded by the Korean government (M10644000005-06N4400-00510 & NRF-2015R1A2A2A01003564). All authors had full access to the data of the study as well as final responsibility for the decision to submit for publication. | en_US |
dc.language.iso | en | en_US |
dc.publisher | KOREAN NEUROPSYCHIATRIC ASSOC | en_US |
dc.subject | Gamma-band activity | en_US |
dc.subject | High-beta-band activity | en_US |
dc.subject | Phase synchronization | en_US |
dc.subject | Schizophrenia | en_US |
dc.subject | Human faces | en_US |
dc.title | Dysfunctional Patterns of Gamma-Band Activity in Response to Human Faces Compared to Non-Facial Stimuli in Patients with Schizophrenia | en_US |
dc.type | Article | en_US |
dc.relation.no | 3 | - |
dc.relation.volume | 13 | - |
dc.identifier.doi | 10.4306/pi.2016.13.3.349 | - |
dc.relation.page | 349-359 | - |
dc.relation.journal | PSYCHIATRY INVESTIGATION | - |
dc.contributor.googleauthor | Lee, Seung-Hwan | - |
dc.contributor.googleauthor | Kim, Sangrae | - |
dc.contributor.googleauthor | Shim, Mi-Seon | - |
dc.contributor.googleauthor | Kim, Do-Won | - |
dc.contributor.googleauthor | Im, Chang-Hwan | - |
dc.relation.code | 2016014267 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF ENGINEERING[S] | - |
dc.sector.department | DIVISION OF ELECTRICAL AND BIOMEDICAL ENGINEERING | - |
dc.identifier.pid | ich | - |
dc.identifier.orcid | http://orcid.org/0000-0003-3795-3318 | - |
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