Dose-Volume Analysis of Lung and Heart according to Respiration in Breast Cancer Patients Treated with Breast Conserving Surgery
- Title
- Dose-Volume Analysis of Lung and Heart according to Respiration in Breast Cancer Patients Treated with Breast Conserving Surgery
- Author
- 김찬형
- Keywords
- Breast neoplasms; Heart; Lung; Radiotherapy
- Issue Date
- 2012-03
- Publisher
- Korean Breast Cancer SOC
- Citation
- Journal of Breast Cancer, 2012, 15(1), P.105-110
- Abstract
- Purpose: Adjuvant radiotherapy of breast cancer using a photon tangential field incurs a risk of late heart and lung toxicity. The use of free breathing (FB), expiration breath hold (EBH), and deep inspiration breath hold (DIBH) during tangential breast radiotherapy as a means of reducing irradiated lung and heart volume was evaluated. Methods: In 10 women with left-sided breast cancer (mean age, 44 years) post-operative computed tomography (CT) scanning was done under different respiratory conditions using FB, EBH, and DIBH in 3 CT scans. For each scan, an optimized radiotherapy plan was designed with 6 MV photon tangential fields encompassing the clinical target volume after breast-conserving surgery. Results: The results of dose-volume histograms were compared using three breathing pattern techniques for the irradiated volume and dose to the heart. A significant reduction dose to the irradiated heart volume for the DIBH breathing technique was compared to FB and EBH breathing techniques (p<0.05). Conclusion: This study demonstrated that the irradiated heart volume can be significantly reduced in patients with left-sided breast cancer using the DIBH breathing technique for tangential radiotherapy.
- URI
- https://synapse.koreamed.org/DOIx.php?id=10.4048/jbc.2012.15.1.105
- ISSN
- 1738-6756
- DOI
- 10.4048/jbc.2012.15.1.105
- Appears in Collections:
- COLLEGE OF ENGINEERING[S](공과대학) > NUCLEAR ENGINEERING(원자력공학과) > Articles
- Files in This Item:
- jbc-15-105.pdfDownload
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