Intramolecular Fischer Indole Synthesis in Combination with Alkyne Hydroarylation: Synthesis of Tetracyclic Chromeno-indoles
- Title
- Intramolecular Fischer Indole Synthesis in Combination with Alkyne Hydroarylation: Synthesis of Tetracyclic Chromeno-indoles
- Author
- 조천규
- Keywords
- (-)-N-METHYLWELWITINDOLINONE C ISOTHIOCYANATE; BOC ARYL HYDRAZINES; REARRANGEMENT REACTIONS; DIRECT OXIDATIONS; AZOBENZENES; CARBOCYCLES; ALKENES; HALIDES; ROUTE; GOLD
- Issue Date
- 2014-01
- Publisher
- AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA
- Citation
- ORGANIC LETTERS 권: 16 호: 1 페이지: 178-181
- Abstract
- Aryl hydrazides bearing a carbonyl function connected through an alkyne tether underwent an intramolecular Fischer indolization and alkyne hydroarylation in a tandem fashion to afford novel tetracyclic chromeno-indoles. The accompanying isomerization of the 2H-chromene double bond can be avoided by stopping the tandem process at the indolophane stage and conducting the alkyne-hydroarylation reaction separately in the absence of a proton source.
- URI
- https://pubs.acs.org/doi/10.1021/ol4031638http://hdl.handle.net/20.500.11754/47363
- ISSN
- 1523-7060
- DOI
- 10.1021/ol4031638
- Appears in Collections:
- COLLEGE OF NATURAL SCIENCES[S](자연과학대학) > CHEMISTRY(화학과) > Articles
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