Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Justyn Wayne Jaworski | - |
dc.date.accessioned | 2018-02-22T12:48:48Z | - |
dc.date.available | 2018-02-22T12:48:48Z | - |
dc.date.issued | 2012-06 | - |
dc.identifier.citation | NEW JOURNAL OF CHEMISTRY,Vol.36 No.8 [2012],p1616-162 | en_US |
dc.identifier.issn | 1144-0546 | - |
dc.identifier.uri | http://pubs.rsc.org/en/Content/ArticleLanding/2012/NJ/c2nj20976d#!divAbstract | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/40154 | - |
dc.description.abstract | Mesoporous hollow silica nanoparticles were functionalized with phenanthroline (P-MHS) to prepare a carrier for a host-guest complex. Curcumin was selected as a model drug molecule. The phenanthroline attached to the P-MHS was complexed with Cu2+ through a coordination bond. When the Cu2+-P-MHS was exposed to similar to pH 5, the curcumin was efficiently released into the aqueous phase within 120 min. This work describes a method for functionalizing the surface of the porous silica nanoparticles in a well-defined manner. The P-MHS carrier exhibited controlled release of a model drug under acidic pH conditions. | en_US |
dc.description.sponsorship | This work was supported by a grant from the NRF (grant no. 2011-0003118) and the World Class University (WCU) Program (R32-2008-000-20003-0) supported by Ministry of Education, Science and Technology, S. Korea. In addition, this work was partially supported by a grant from the Next-Generation BioGreen 21 Program (SSAC, grant no. PJ009041), Rural Development Administration, S. Korea. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Royal Society of Chemistry | en_US |
dc.subject | SENSITIVE LIPOSOMES | en_US |
dc.subject | POLYMERIC MICELLES | en_US |
dc.subject | NANOPARTICLES; CURCUMIN | en_US |
dc.subject | THERAPEUTICS | en_US |
dc.subject | ORGANOSILICA | en_US |
dc.subject | NANOSPHERES | en_US |
dc.subject | HYDROGELS | en_US |
dc.subject | VESICLES; CARRIERS | en_US |
dc.title | Controlled drug delivery from mesoporous silica using a pH-response release system | en_US |
dc.type | Article | en_US |
dc.relation.no | 8 | - |
dc.relation.volume | 36 | - |
dc.identifier.doi | 10.1039/c2nj20976d | - |
dc.relation.page | 1616-1620 | - |
dc.relation.journal | NEW JOURNAL OF CHEMISTRY | - |
dc.contributor.googleauthor | Jin, Dalsaem | - |
dc.contributor.googleauthor | Lee, Ji Ha | - |
dc.contributor.googleauthor | Seo, Moo Lyong | - |
dc.contributor.googleauthor | Jaworski, Justyn | - |
dc.contributor.googleauthor | Jung, Jong Hwa | - |
dc.relation.code | 2012207075 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF ENGINEERING[S] | - |
dc.sector.department | DEPARTMENT OF CHEMICAL ENGINEERING | - |
dc.identifier.pid | justynj | - |
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