Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 서미란 | - |
dc.date.accessioned | 2018-02-12T08:49:42Z | - |
dc.date.available | 2018-02-12T08:49:42Z | - |
dc.date.issued | 2011-07 | - |
dc.identifier.citation | Journal of Korean Medical Science, 2011, 26(10), P.1258-1264 | en_US |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://synapse.koreamed.org/DOIx.php?id=10.3346/jkms.2011.26.10.1258 | - |
dc.description.abstract | In order to investigate the incidence, clinical and microbiologic characteristics of Clostridium difficile infection (CDI) in Korea, a prospective observational study was performed. From September 2008 through January 2010, all patients whose stool was tested for toxin assay A&B and/or C. difficile culture were studied for clinical characteristics. Toxin types of the isolates from stool were tested. The mean incidence of CDI per 100,000 patient-days was 71.6 by month (range, 52.5-114.0), and the ratio of CDI to antibiotic-associated diarrhea was 0.23. Among 200 CDI patients, 37.5% (75/200) was severe CDI based on severity score. Clinical outcome of 189 CDI was as followed; 25.9% (49/189) improved without treatment, 84.3% (118/140) achieved clinical cure and attributed mortality was 0.7% (1/140) with the treatment. Recurrence rate was 21.4% (30/140) and cure without recurrence was 66.4% (93/140). The most common type of toxin was toxin A-positive/toxin B-positive strain (77.5%), toxin A-negative/toxin B-positive strains or binary toxin-producing strains comprised 15.4% or 7.1%, respectively. In conclusion, the incidence of CDI in Korea is a little higher than other reports during the non-epidemic setting. We expect that the change of epidemiology and clinical severity in CDI can be evaluated based on these results. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Korean ACDC Medical Science | en_US |
dc.subject | Clostridium difficile Infection | en_US |
dc.subject | Incidence | en_US |
dc.subject | Clinical Characteristics | en_US |
dc.subject | Toxin Type | en_US |
dc.subject | ANTIMICROBIAL RESISTANCE | en_US |
dc.subject | MOLECULAR EPIDEMIOLOGY | en_US |
dc.subject | TOXIN | en_US |
dc.subject | DIARRHEA | en_US |
dc.subject | STRAINS | en_US |
dc.subject | PREVALENCE | en_US |
dc.subject | FEATURES | en_US |
dc.title | Epidemiology and Clinical Characteristics of Clostridium difficile Infection in a Korean Tertiary Hospital | en_US |
dc.type | Article | en_US |
dc.relation.volume | 26 | - |
dc.identifier.doi | 10.3346/jkms.2011.26.10.1258 | - |
dc.relation.page | 1258-1264 | - |
dc.relation.journal | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.contributor.googleauthor | Kang, Jung Oak | - |
dc.contributor.googleauthor | Pai, Hyunjoo | - |
dc.contributor.googleauthor | Pai, Hyunjoo | - |
dc.contributor.googleauthor | Seo, Mi-ran | - |
dc.contributor.googleauthor | Kim, Jieun | - |
dc.contributor.googleauthor | Kang, Jung Oak | - |
dc.relation.code | 2011212229 | - |
dc.sector.campus | S | - |
dc.sector.daehak | RESEARCH INSTITUTE[S] | - |
dc.sector.department | INSTITUTE FOR THE INTERGRATION OF MEDICINE AND INNOVATIVE TECHNOLOGY | - |
dc.identifier.pid | thorn9997 | - |
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