Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이종민 | - |
dc.date.accessioned | 2017-08-09T01:49:38Z | - |
dc.date.available | 2017-08-09T01:49:38Z | - |
dc.date.issued | 2015-10 | - |
dc.identifier.citation | ALZHEIMER DISEASE & ASSOCIATED DISORDERS, v. 29, NO 4, Page. 279-286 | en_US |
dc.identifier.issn | 0893-0341 | - |
dc.identifier.uri | http://pt.wkhealth.com/pt/re/lwwgateway/landingpage.htm;jsessionid=ZJXYDqVLvLNBysGy6hyQKQGvF776YhyfLTsJnfsXh4qxcxKQyPn1!721960586!181195628!8091!-1?sid=WKPTLP:landingpage&an=00002093-201510000-00002 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/28389 | - |
dc.description.abstract | Background:Increasing evidence has emerged that there is a link between body weight and the risk of developing dementia. However, the relationship between adiposity and brain structure has not yet been fully elucidated. We aimed to evaluate the association of body fat composition with cortical thickness in cognitively normal subjects.Methods:In total, 1777 (887 men and 890 women) cognitively normal subjects, aged 45 years or older, were recruited from the Health Promotion Center in South Korea. Medical records including 3-dimensional magnetic resonance imaging, body fat percentage, waist-hip ratio (WHR), and other factors were reviewed.Results:In men, the percentage of fat was positively associated with cortical thickness and the highest WHR group showed significantly decreased cortical thickness compared with the reference group. WHR showed an inverted U-shaped association with total cortical thickness and frontal lobe thickness in men. Among women, there was no significant association.Conclusions:Our findings suggest that in men, body fat is positively associated with cortical thickness, whereas abdominal fat is negatively associated with cortical thickness. | en_US |
dc.description.sponsorship | Supported by grants from the Korea Healthcare Technology R&D Project, Ministry of Health and Welfare, Republic of Korea [HIC120713, HI10C2020]; the Korea Ministry of Environment (MOE) as the Environmental Health Action Program (2014001360002); the Korean Science and Engineering Foundation (KOSEF) NRL program funded by the Korean government [MEST; 2011-0028333]; a Samsung Medical Center Clinical Research Development Program grant [CRL-108011 & CRS 110-14-1]; and the Converging Research Center Program through the Ministry of Science, ICT and Future Planning, Korea [2013K000338]. | en_US |
dc.language.iso | en | en_US |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | en_US |
dc.subject | cortical thickness | en_US |
dc.subject | body fat percentage | en_US |
dc.subject | waist hip ratio | en_US |
dc.subject | MRI | en_US |
dc.subject | surface-based morphometric analysis | en_US |
dc.title | Association of Body Fat Percentage and Waist-hip Ratio With Brain Cortical Thickness A Study Among 1777 Cognitively Normal Subjects | en_US |
dc.type | Article | en_US |
dc.relation.no | 4 | - |
dc.relation.volume | 29 | - |
dc.identifier.doi | 10.1097/WAD.0000000000000079 | - |
dc.relation.page | 279-286 | - |
dc.relation.journal | ALZHEIMER DISEASE & ASSOCIATED DISORDERS | - |
dc.contributor.googleauthor | Kim, Hee Jin | - |
dc.contributor.googleauthor | Kim, Changsoo | - |
dc.contributor.googleauthor | Jeon, Seun | - |
dc.contributor.googleauthor | Kang, Mira | - |
dc.contributor.googleauthor | Kim, Yeo Jin | - |
dc.contributor.googleauthor | Lee, Jong-Min | - |
dc.contributor.googleauthor | Shin, Hee-Young | - |
dc.contributor.googleauthor | Cho, Hanna | - |
dc.contributor.googleauthor | Ye, Byoung Seok | - |
dc.contributor.googleauthor | Kim, Jung-Hyun | - |
dc.relation.code | 2015000021 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF ENGINEERING[S] | - |
dc.sector.department | DIVISION OF ELECTRICAL AND BIOMEDICAL ENGINEERING | - |
dc.identifier.pid | ljm | - |
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