Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 오제훈 | - |
dc.date.accessioned | 2024-06-24T01:25:25Z | - |
dc.date.available | 2024-06-24T01:25:25Z | - |
dc.date.issued | 2024-04-11 | - |
dc.identifier.citation | SCIENTIFIC REPORTS, v. 14, article no. 8476, page. 1-12 | en_US |
dc.identifier.issn | 2045-2322 | en_US |
dc.identifier.uri | https://www.nature.com/articles/s41598-024-59042-2 | en_US |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/190926 | - |
dc.description.abstract | Computational fluid dynamics (CFD) has been utilized to calculate hemodynamic parameters in anterior communicating artery aneurysm (AComA), which is located at a junction between left and right A1 and A2 segments. However, complete or half circle of Willis (CoW) models are used indiscriminately. This study aims to suggest recommendations for determining suitable CoW model. Five patient-specific CoW models with AComA were used, and each model was divided into complete, left-half, and right-half models. After validating the CFD using a flow experiment, the hemodynamic parameters and flow patterns in five AComAs were compared. In four out of five cases, inflow from one A1 side had a dominant influence on the AComA, while both left and right A1 sides affected the AComA in the remaining case. Also, the average difference in time-averaged wall shear stress between the complete and half models for four cases was 4.6%, but it was 62% in the other case. The differences in the vascular resistances of left and right A1 and A2 segments greatly influenced the flow patterns in the AComA. These results may help to enhance clinicians' understanding of blood flow in the brain, leading to improvements in diagnosis and treatment of cerebral aneurysms. | en_US |
dc.description.sponsorship | Tis work was supported by a National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT) (No. 2020R1A2C1011918). It was also supported by the Basic Science Research Program through the NRF funded by the Ministry of Education (No. 2021R1I1A1A01059964). | en_US |
dc.language | en_US | en_US |
dc.publisher | NATURE PORTFOLIO | en_US |
dc.relation.ispartofseries | v. 14, article no. 8476;1-12 | - |
dc.subject | Circle of Willis | en_US |
dc.subject | Anterior communicating artery aneurysms | en_US |
dc.subject | Computational fuid dynamics | en_US |
dc.subject | Hemodynamic parameters | en_US |
dc.subject | Vascular resistance | en_US |
dc.title | Influence of circle of Willis modeling on hemodynamic parameters in anterior communicating artery aneurysms and recommendations for model selection | en_US |
dc.type | Article | en_US |
dc.relation.no | 1 | - |
dc.relation.volume | 14 | - |
dc.identifier.doi | https://doi.org/10.1038/s41598-024-59042-2 | en_US |
dc.relation.page | 8476-8476 | - |
dc.relation.journal | SCIENTIFIC REPORTS | - |
dc.contributor.googleauthor | Yang, Hyeondong | - |
dc.contributor.googleauthor | Cho, Kwang‑Chun | - |
dc.contributor.googleauthor | Hong, Ineui | - |
dc.contributor.googleauthor | Kim, Yeonwoo | - |
dc.contributor.googleauthor | Kim, Yong Bae | - |
dc.contributor.googleauthor | Kim, Jung‑Jae | - |
dc.contributor.googleauthor | Oh, Je Hoon | - |
dc.relation.code | 2024009170 | - |
dc.sector.campus | E | - |
dc.sector.daehak | COLLEGE OF ENGINEERING SCIENCES[E] | - |
dc.sector.department | DEPARTMENT OF MECHANICAL ENGINEERING | - |
dc.identifier.pid | jehoon | - |
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