Synthesis of L-Ribose from D-Ribose by a Stereoconversion through Sequential Lactonization as the Key Transformation
- Title
- Synthesis of L-Ribose from D-Ribose by a Stereoconversion through Sequential Lactonization as the Key Transformation
- Author
- 이학준
- Keywords
- L-ribose; D-ribose; sugar; lactonization; DIBAL-H; reduction
- Issue Date
- 2017-09
- Publisher
- Georg Thieme Verlag
- Citation
- Synthesis, v. 49, NO. 18, Page. 4299-4302
- Abstract
- Ribose, a key precursor of various L-nucleosides can only be synthesized from other sugars or other non-sugar precursors. Herein, the study involves the synthesis of naturally rare L-ribose from readily available D-ribose. Though, many synthetic strategies are developed to meet the increasing demands of L-ribose, seeking innovation, a synthesis employing sequential lactonization as the key transformation was explored. This novel conversion involves protection, oxidation, sequential lactonization, reduction with DIBAL-H, and deprotection.
- URI
- https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0036-1588857https://repository.hanyang.ac.kr/handle/20.500.11754/183962
- ISSN
- 0039-7881;1437-210X
- DOI
- 10.1055/s-0036-1588857
- Appears in Collections:
- COLLEGE OF SCIENCE AND CONVERGENCE TECHNOLOGY[E](과학기술융합대학) > CHEMICAL AND MOLECULAR ENGINEERING(화학분자공학과) > Articles
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