Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 조용우 | - |
dc.date.accessioned | 2023-07-17T01:19:17Z | - |
dc.date.available | 2023-07-17T01:19:17Z | - |
dc.date.issued | 2011-06 | - |
dc.identifier.citation | JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, v. 97A, NO. 3, Page. 292-299 | - |
dc.identifier.issn | 1549-3296;1552-4965 | - |
dc.identifier.uri | https://onlinelibrary.wiley.com/doi/10.1002/jbm.a.33056 | en_US |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/183764 | - |
dc.description.abstract | Decellularized tissues composed of extracellular matrix (ECM) have been clinically used to support the regeneration of various human tissues and organs. Most decellularized tissues so far have been derived from animals or cadavers. Therefore, despite the many advantages of decellularized tissue, there are concerns about the potential for immunogenicity and the possible presence of infectious agents. Herein, we present a biomaterial composed of ECM derived from human adipose tissue, the most prevalent, expendable, and safely harvested tissue in the human body. The ECM was extracted by successive physical, chemical, and enzymatic treatments of human adipose tissue isolated by liposuction. Cellular components including nucleic acids were effectively removed without significant disruption of the morphology or structure of the ECM. Major ECM components were quantified, including acid/pepsin-soluble collagen, sulfated glycosaminoglycan (GAG), and soluble elastin. In an in vivo experiment using mice, the decellularized ECM graft exhibited good compatibility to surrounding tissues. Overall results suggest that the decellularized ECM containing biological and chemical cues of native human ECM could be an ideal scaffold material not only for autologous but also for allograft tissue engineering. (C) 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 97A: 292-299, 2011. | - |
dc.language | en | - |
dc.publisher | WILEY-BLACKWELL | - |
dc.subject | extracellular matrix | - |
dc.subject | scaffold | - |
dc.subject | tissue engineering | - |
dc.subject | adipose tissue | - |
dc.subject | allograft | - |
dc.title | Decellularized extracellular matrix derived from human adipose tissue as a potential scaffold for allograft tissue engineering | - |
dc.type | Article | - |
dc.relation.no | 3 | - |
dc.relation.volume | 97A | - |
dc.identifier.doi | 10.1002/jbm.a.33056 | - |
dc.relation.page | 292-299 | - |
dc.relation.journal | JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A | - |
dc.contributor.googleauthor | Choi, Ji Suk | - |
dc.contributor.googleauthor | Kim, Beob Soo | - |
dc.contributor.googleauthor | Kim, Jun Young | - |
dc.contributor.googleauthor | Kim, Jae Dong | - |
dc.contributor.googleauthor | Choi, Young Chan | - |
dc.contributor.googleauthor | Yang, Hyun-Jin | - |
dc.contributor.googleauthor | Park, Kinam | - |
dc.contributor.googleauthor | Lee, Hee Young | - |
dc.contributor.googleauthor | Cho, Yong Woo | - |
dc.sector.campus | E | - |
dc.sector.daehak | 공학대학 | - |
dc.sector.department | 재료화학공학과 | - |
dc.identifier.pid | ywcho7 | - |
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