Decision supporting frame to estimate chronic exposure suspicion to VOC chemicals using mixed statistical model
- Title
- Decision supporting frame to estimate chronic exposure suspicion to VOC chemicals using mixed statistical model
- Author
- 황승용
- Keywords
- Decision supporting system; Discriminant analysis; VOC; Cross-validation
- Issue Date
- 2013-03
- Publisher
- 대한독성 유전단백체 학회
- Citation
- Molecular & Cellular Toxicology, v. 9, NO. 1, Page. 75-83
- Abstract
- In this paper, we examine the model for a chemical exposure decision support algorithm. Our purpose is to suggest the model frame to describe possibility of exposure with low-dose VOC chemicals for long time under normal circumstances at working place. Forensic rhetoric terms, non-exclusion exposure suspicion (NES) and exclusion exposure suspicion (EES), were defined and various statistical methods were combined basis of Bayesian approach. Decision-tree (DT) methods of linear discriminant analysis (LDA), quadratic discriminant analysis (QDA), and naive Bayes model were evaluated to classify 3 VOCs (toluene, xylene, and ehtybenzene) by means of the results of urinary test, gene expression and methylation expression experiments. Overall procedure is conducted by leave-one-out cross-validation that error rate of NES resulted in 11%.
- URI
- https://link.springer.com/article/10.1007/s13273-013-0011-6https://repository.hanyang.ac.kr/handle/20.500.11754/181618
- ISSN
- 1738-642X;2092-8467
- DOI
- 10.1007/s13273-013-0011-6
- Appears in Collections:
- COLLEGE OF SCIENCE AND CONVERGENCE TECHNOLOGY[E](과학기술융합대학) > ETC
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