Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 임창환 | - |
dc.date.accessioned | 2022-12-06T07:07:01Z | - |
dc.date.available | 2022-12-06T07:07:01Z | - |
dc.date.issued | 2021-05 | - |
dc.identifier.citation | SCIENTIFIC REPORTS, v. 11, NO. 1, article no. 9745, Page. 1-11 | en_US |
dc.identifier.issn | 2045-2322 | en_US |
dc.identifier.uri | https://www.nature.com/articles/s41598-021-89243-y | en_US |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/178056 | - |
dc.description.abstract | Transorbital electrical stimulation (tES) has been studied as a new noninvasive method for treating intractable eye diseases by delivering weak electrical current to the eye through a pair of electrodes attached to the skin around the eye. Studies have reported that the therapeutic effect of tES is determined by the effective stimulation of retinal cells that are densely distributed in the posterior part of the retina. However, in conventional tES with a pair of electrodes, a greater portion of the electric field is delivered to the anterior part of the retina. In this study, to address this issue, a new electrode montage with multiple electrodes was proposed for the effective delivery of electric fields to the posterior retina. Electric field analysis based on the finite element method was performed with a realistic human head model, and optimal injection currents were determined using constrained convex optimization. The resultant electric field distributions showed that the proposed multi-channel tES enables a more effective stimulation of the posterior retina than the conventional tES with a pair of electrodes. | en_US |
dc.description.sponsorship | This work was supported in part by a Grant from the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (Grant number: HI17C1501), and in part by the Brain Research Program through the National Research Foundation of Korea (NRF), funded by the Ministry of Science, ICT & Future Planning (no. NRF-2019M3C7A1031278). | en_US |
dc.language | en | en_US |
dc.publisher | NATURE RESEARCH | en_US |
dc.source | 80174_임창환.pdf | - |
dc.title | Multi-channel transorbital electrical stimulation for effective stimulation of posterior retina | en_US |
dc.type | Article | en_US |
dc.relation.no | 1 | - |
dc.relation.volume | 11 | - |
dc.identifier.doi | 10.1038/s41598-021-89243-y | en_US |
dc.relation.page | 1-11 | - |
dc.relation.journal | SCIENTIFIC REPORTS | - |
dc.contributor.googleauthor | Lee, Sangjun | - |
dc.contributor.googleauthor | Park, Jimin | - |
dc.contributor.googleauthor | Kwon, Jinuk | - |
dc.contributor.googleauthor | Kim, Dong Hwan | - |
dc.contributor.googleauthor | Im, Chang-Hwan | - |
dc.sector.campus | S | - |
dc.sector.daehak | 공과대학 | - |
dc.sector.department | 바이오메디컬공학전공 | - |
dc.identifier.pid | ich | - |
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