Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 설원제 | - |
dc.date.accessioned | 2022-10-12T00:32:53Z | - |
dc.date.available | 2022-10-12T00:32:53Z | - |
dc.date.issued | 2021-01 | - |
dc.identifier.citation | IEEE SENSORS JOURNAL, v. 21, no. 1, Page. 178-184 | en_US |
dc.identifier.issn | 1530-437X; 1558-1748 | en_US |
dc.identifier.uri | https://ieeexplore.ieee.org/document/9159616 | en_US |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/175224 | - |
dc.description.abstract | We report on a stable and sensitive biochemical sensor based on amorphous indium-gallium-zinc-oxide (a-IGZO) thin-film transistors (TFTs) with a versatile extended-gate electrode used as the sensing membrane. The extended-gate allows the active transistor channel not to be exposed to the ionic analyte and the gate surface may be modified with chemicals or affinity reagents without affecting the operation of the active sensor. The extended-gate a-IGZO TFT was able to detect the pH levels of various solutions based on protonation and deprotonation at the surface of the indium-tin-oxide (ITO) extended-gate electrode achieving a pH dependent threshold voltage shift of 22.8 mV/pH. Highly sensitive and specific protein sensing was achieved for both electrical polarities according to pH values of solutions using the biotin-streptavidin interaction. The extended-gate TFT sensor demonstrated a detection limit for streptavidin down to 10 fM, using the biotin-streptavidin binding on the extended-gate surface. It was also possible to detect changes in the streptavidin concentration in real-time with specificity and repeatability. Since the extended-gate can be easily replaced without affecting the performance of the a-IGZO TFT, this sensor configuration may be utilized for future multifunctional biomolecular sensing and analysis. | en_US |
dc.description.sponsorship | This work was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF), funded in part by the Ministry of Science and ICT under Grant NRF-2014M3A7B4049369, Grant NRF-2017R1A2B4003189 and Grant NRF-2020R1F1A1073325, and in part by the Ministry of Education of Korea under Grant NRF-2012R1A6A1029029 and Grant NRF-2019R1I1A1A01057620. | en_US |
dc.language.iso | en | en_US |
dc.publisher | IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC | en_US |
dc.subject | Biosensors; extended-gate field-effect transistors; pH sensors; real-time detection; thin film transistors | en_US |
dc.title | Extended-Gate Amorphous InGaZnO Thin Film Transistor for Biochemical Sensing | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1109/JSEN.2020.3014447 | en_US |
dc.relation.page | 178-184 | - |
dc.relation.journal | IEEE SENSORS JOURNAL | - |
dc.contributor.googleauthor | Lee, Jusin | - |
dc.contributor.googleauthor | Kim, Min Jae | - |
dc.contributor.googleauthor | Yang, Heewon | - |
dc.contributor.googleauthor | Kim, Sunjin | - |
dc.contributor.googleauthor | Yeom, Seongoh | - |
dc.contributor.googleauthor | Ryu, Gunwoo | - |
dc.contributor.googleauthor | Shin, Yoonsoo | - |
dc.contributor.googleauthor | Sul, Onejae | - |
dc.contributor.googleauthor | Jeong, Jae Kyeong | - |
dc.contributor.googleauthor | Lee, Seung-Beck | - |
dc.relation.code | 2021001285 | - |
dc.sector.campus | S | - |
dc.sector.daehak | RESEARCH INSTITUTE[S] | - |
dc.sector.department | INSTITUTE OF NANO SCIENCE AND TECHNOLOGY | - |
dc.identifier.pid | ojsul | - |
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