Comparing effectiveness of polydeoxyribonucleotide injection and corticosteroid injection in plantar fasciitis treatment: A prospective randomized clinical study
- Title
- Comparing effectiveness of polydeoxyribonucleotide injection and corticosteroid injection in plantar fasciitis treatment: A prospective randomized clinical study
- Author
- 조형래
- Keywords
- Plantar fasciitis; Conservative treatment; Injection; Polydeoxyribonucleotide (PDRN); Corticosteroid
- Issue Date
- 2020-08
- Publisher
- ELSEVIER
- Citation
- FOOT AND ANKLE SURGERY, v. 26, no. 6, page. 657-661
- Abstract
- Background: This study aimed to compare the efficacy and safety of polydeoxyribonucleotide (PDRN) injection and corticosteroid injection for plantar fasciitis.
Methods: This study included 44 patients with plantar fasciitis, randomly allocated to the PDRN and corticosteroid groups. Evaluation using the visual analogue scale (VAS) pain score and Manchester-Oxford foot questionnaire (MOXFQ) was conducted at baseline, 1, 2, 6 weeks and 6 months. The thickness and echogenicity of the plantar fascia in ultrasonography and complications were recorded.
Results: Corticosteroid injection elicited more pain relief than did PDRN injection at 2 (p =0.010) and 6 weeks (p= 0.016); however, it showed no superiority at 6 months (p =0.523). MOXFQ showed similar outcomes. The thickness and echogenicity did not differ between groups and no complications were reported in either group.
Conclusions: We demonstrated that PDRN injection could be an effective and safe option for plantar fasciitis and was comparable to corticosteroid injection after 6 months follow up. (C) 2019 European Foot and Ankle Society. Published by Elsevier Ltd. All rights reserved.
- URI
- https://www.sciencedirect.com/science/article/pii/S1268773119301377?via%3Dihubhttps://repository.hanyang.ac.kr/handle/20.500.11754/170351
- ISSN
- 1268-7731; 1460-9584
- DOI
- 10.1016/j.fas.2019.08.005
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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