Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 조용우 | - |
dc.date.accessioned | 2021-12-23T03:57:26Z | - |
dc.date.available | 2021-12-23T03:57:26Z | - |
dc.date.issued | 2021-02 | - |
dc.identifier.citation | JOURNAL OF CONTROLLED RELEASE, v. 330, Page. 15-30 | en_US |
dc.identifier.issn | 0168-3659 | - |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0168365920307197 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/166976 | - |
dc.description.abstract | The biological significance of extracellular vesicles (EVs) as intercellular communication mediators has been increasingly revealed in a wide range of normal physiological processes and disease pathogenesis. In particular, regenerative and immunomodulatory EVs hold potential as innate biotherapeutics, whereas pathological EVs are considered therapeutic targets for inhibiting their bioactivity. Given their ability to transport functional cargos originating from the source cells to target cells, EVs can also be used as a therapeutic means to deliver drug molecules. This review aims to provide an updated overview of the key engineering approaches for better exploiting EVs in disease intervention. The emphasis is lying on the preconditioning methods for therapeutic EVs, drug loading and targeting technologies for carrier EVs, and activity control strategies for pathological EVs. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | ELSEVIER | en_US |
dc.subject | Extracellular vesicles | en_US |
dc.subject | Therapeutic applications | en_US |
dc.subject | Preconditioning | en_US |
dc.subject | Drug loading | en_US |
dc.subject | Surface modification | en_US |
dc.subject | Biogenesis inhibition | en_US |
dc.title | Engineering approaches for effective therapeutic applications based on extracellular vesicles | en_US |
dc.type | Article | en_US |
dc.relation.volume | 330 | - |
dc.identifier.doi | 10.1016/j.jconrel.2020.11.062 | - |
dc.relation.page | 15-30 | - |
dc.relation.journal | JOURNAL OF CONTROLLED RELEASE | - |
dc.contributor.googleauthor | Kwon, Seunglee | - |
dc.contributor.googleauthor | Shin, Sol | - |
dc.contributor.googleauthor | Do, Minjae | - |
dc.contributor.googleauthor | Oh, Byeong Hoon | - |
dc.contributor.googleauthor | Song, Yeari | - |
dc.contributor.googleauthor | Bui, Van Dat | - |
dc.contributor.googleauthor | Lee, Eun Sook | - |
dc.contributor.googleauthor | Jo, Dong-Gyu | - |
dc.contributor.googleauthor | Kim, Deok-Ho | - |
dc.contributor.googleauthor | Park, Jae Hyung | - |
dc.contributor.googleauthor | Cho, Yong Woo | - |
dc.relation.code | 2021004235 | - |
dc.sector.campus | E | - |
dc.sector.daehak | COLLEGE OF ENGINEERING SCIENCES[E] | - |
dc.sector.department | DEPARTMENT OF MATERIALS SCIENCE AND CHEMICAL ENGINEERING | - |
dc.identifier.pid | ywcho7 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.