In vitro Evaluation of Carbon-based Nanospheres as Drug Delivery Vesicles in Breast Cancer Cell

Abstract

The application of nanoparticles in cancer treatment allows precise tumor treatment by enhancing drug delivery to the tumor area. To overcome limitations in the drug delivery system, we report carbon-based nanospheres (CSs) that have high drug loading capacity as well as anti-cancer effects. Monodisperse and size-tunable (170–583 nm) CSs with excellent surface area up to 2619 m2 /g provided high drug loading capacity in four different types of drugs (doxorubicin, gemcitabine, docetaxel, and paclitaxel), and demonstrated strong anti-cancer effects against MDA-MB-231 human breast carcinoma cells.