Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 문성용 | - |
dc.date.accessioned | 2020-10-12T06:14:38Z | - |
dc.date.available | 2020-10-12T06:14:38Z | - |
dc.date.issued | 2019-10 | - |
dc.identifier.citation | JOURNAL OF CHROMATOGRAPHY A, v. 1603, Page. 388-395 | en_US |
dc.identifier.issn | 0021-9673 | - |
dc.identifier.issn | 1873-3778 | - |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0021967319306090?via%3Dihub | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/154521 | - |
dc.description.abstract | For a simulated moving bed (SMB) chromatographic process, it has been common knowledge that as desorbent usage increases, the level of separation capability (i.e., the purity and recovery of a target product) continues to improve and then eventually reaches almost a constant level. To check whether there are any exceptional cases concerning such a generally accepted relationship, the effect of desorbent usage on the recovery of a target product under the condition of high purity was investigated using a three-zone SMB process for separation of xylobiose (X2) from a beta-xylosidase reaction output. It was found that the considered SMB represented some unusual relationship between desorbent usage and X2 recovery, which also took quite a different pattern according to the searching region for optimal SMB operation parameters. If the optimal operation parameters are determined in the region of positive flow-rateratios ("m(+) approach"), the use of a larger amount of desorbent than required to make X2 recovery reach a constant level can rather lead to a little reduction in X2 recovery. If the optimal operation parameters are selected in the region of negative flow-rate-ratios ("M- approach"), there exists an optimal desorbent usage, beyond which a further increase in desorbent usage can bring about a significant reduction in X2 recovery. Comparison of the two design approaches reveals that the m(-) approach can lead to higher X2 recovery and much lower desorbent usage than the m(+) approach. Furthermore, such merits of the m(-) approach over the m(+) approach became greater with increasing the SMB throughput. (C) 2019 Elsevier B.V. All rights reserved. | en_US |
dc.description.sponsorship | This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT (grant number NRF-2019R1H1A2039671). Also, it was partially supported by the Advanced Biomass R&D Center (ABC) of Global Frontier Project funded by the Ministry of Science and ICT (ABC-2010-0029728). | en_US |
dc.language.iso | en | en_US |
dc.publisher | ELSEVIER SCIENCE BV | en_US |
dc.subject | Simulated moving bed | en_US |
dc.subject | Desorbent usage | en_US |
dc.subject | Product recovery | en_US |
dc.subject | Optimal design | en_US |
dc.title | Relationship between desorbent usage and the recovery of a target product in three-zone simulated moving bed processes designed under the conditions of positive and negative flow-rate-ratios of liquid to solid phases | en_US |
dc.type | Article | en_US |
dc.relation.volume | 1603 | - |
dc.identifier.doi | 10.1016/j.chroma.2019.06.010 | - |
dc.relation.page | 388-395 | - |
dc.relation.journal | JOURNAL OF CHROMATOGRAPHY A | - |
dc.contributor.googleauthor | Mun, Sungyong | - |
dc.relation.code | 2019003274 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF ENGINEERING[S] | - |
dc.sector.department | DEPARTMENT OF CHEMICAL ENGINEERING | - |
dc.identifier.pid | munsy | - |
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