Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 오창호 | - |
dc.date.accessioned | 2020-09-15T02:24:03Z | - |
dc.date.available | 2020-09-15T02:24:03Z | - |
dc.date.issued | 2019-10 | - |
dc.identifier.citation | CHEMISTRYSELECT, v. 4, no. 40, Page. 11926-11929 | en_US |
dc.identifier.issn | 2365-6549 | - |
dc.identifier.uri | https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/slct.201903404 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/153916 | - |
dc.description.abstract | An efficient approach towards the total synthesis of Taxamairin B has been accomplished within 6 steps starting from o-bromobenzylbromide 7 with 45% overall yield. Intramolecular Heck reaction works efficiently to furnish the 6-7-6 fused icetexane scaffold under hydrative condition, which on restructuring affords the key beta,gamma-enedione intermediate. The beta,gamma-double bond has been introduced by the acid catalyzed water assisted elimination of a beta-tertiary alcohol. Later, the beta,gamma-enedione on introduction of requisite unsaturation transforms into Taxamairin B. | en_US |
dc.description.sponsorship | This work was supported by a grant from the National Research Foundation of Korea (NRF), funded by the Korean Government, through Individual Research, Mid-career Research Program (NRF2017R1 A2B4003211). | en_US |
dc.language.iso | en | en_US |
dc.publisher | WILEY-V C H VERLAG GMBH | en_US |
dc.subject | Taxamairin | en_US |
dc.subject | Icetaxane | en_US |
dc.subject | Heck reaction | en_US |
dc.subject | natural product | en_US |
dc.subject | total synthesis | en_US |
dc.title | Generation of the Icetexane Core by Use of a Heck Strategy: Total Synthesis of Taxamairin B | en_US |
dc.type | Article | en_US |
dc.relation.no | 40 | - |
dc.relation.volume | 4 | - |
dc.identifier.doi | 10.1002/slct.201903404 | - |
dc.relation.page | 11926-11929 | - |
dc.relation.journal | CHEMISTRYSELECT | - |
dc.contributor.googleauthor | Le, Thuy Quynh | - |
dc.contributor.googleauthor | Karmakar, Swastik | - |
dc.contributor.googleauthor | Lee, Seonmi | - |
dc.contributor.googleauthor | Chai, Uiseong | - |
dc.contributor.googleauthor | Le, Minh Hoang | - |
dc.contributor.googleauthor | Oh, Chang Ho | - |
dc.relation.code | 2019040770 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF NATURAL SCIENCES[S] | - |
dc.sector.department | DEPARTMENT OF CHEMISTRY | - |
dc.identifier.pid | changho | - |
dc.identifier.researcherID | M-6652-2018 | - |
dc.identifier.orcid | https://orcid.org/0000-0002-7208-4261 | - |
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