한국과 미국 50세 이상 성인의 해산물 섭취와 골다공증 위험의 관련성

Abstract

Fish rich in n-3 polyunsaturated fatty acids has been suggested to have favorable effect on bone health, but previous epidemiologic studies showed inconsistent results. The purpose of the present study was to investigate the hypothesis that seafood consumption was associated positively with bone mass and negatively with the risk of osteoporosis in Korean and American. Men and postmenopausal women with ≥ 50 years old were included from Korean National Health and Nutrition Examination Survey 2008-2011 (n=7,154), and National Health and Nutrition Examination Survey 2007-2010 (n=2,658). There was positive correlation between seafood consumption and bone mineral density (BMD) of total femur, femoral neck and lumbar spine in Korean. Consistently, multivariate logistic regression analysis showed the significant association between intake of seafood and the risk of osteoporosis in Korean, but not in American. Seafood consumption was 4-5 times higher in Korean than American in the present study. In conclusion, intake of seafood was associated with BMD and the risk of osteoporosis in Korean but not in American, suggesting that minimum intake level of seafood might be existed to protect from bone loss and osteoporosis.