Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김기현 | - |
dc.date.accessioned | 2019-11-30T19:12:49Z | - |
dc.date.available | 2019-11-30T19:12:49Z | - |
dc.date.issued | 2017-09 | - |
dc.identifier.citation | ACS APPLIED MATERIALS & INTERFACES, v. 9, no. 39, page. 33589-33598 | en_US |
dc.identifier.issn | 1944-8244 | - |
dc.identifier.uri | https://pubs.acs.org/doi/10.1021/acsami.7b07818 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/115708 | - |
dc.description.abstract | To produce a sensitive and specific biosensor for Staphylococcus aureus, bacteriophages have been interfaced with a water-dispersible and environmentally stable metal-organic framework (MOF), NH2-MIL-53(Fe). The conjugation of the MOF with bacteriophages has been achieved through the use of glutaraldehyde as cross-linker. Highly sensitive detection of S. aureus in both synthetic and real samples was realized by the proposed MOF-bacteriophage' biosensor based on the photoluminescence quenching phenomena; limit of detection (31 CFU/mL) and range of detection (40 to 4 X 10(8) CFU/mL). This is the first report exploiting the use of an MOF-bacteriophage complex for the biosensing of S. aureus. The results of our study highlight that-the proposed biosensor is more sensitive than most of the previous methods while exhibiting some advanced features like specificity) regenerability, extended range of linear 'detection, and stability for long-term storage (even at room temperature). | en_US |
dc.description.sponsorship | This work was funded through a CSIR India grant MLP 023. We are grateful to the Director of CSIR-CSIO, Chandigarh, India, for supporting this research. K.H.K. acknowledges support made in part by grants from the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT & Future Planning (No. 2016R1E1A1A01940995). This work was also carried out with the support of "Cooperative Research Program for Agriculture Science and Technology Development (Project No. PJ012521032017)" Rural Development Administration, Republic of Korea. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | AMER CHEMICAL SOC | en_US |
dc.subject | Staphylococcus aureus | en_US |
dc.subject | bacteriophages | en_US |
dc.subject | MOF | en_US |
dc.subject | fluorescence | en_US |
dc.subject | detection | en_US |
dc.title | MOF-Bacteriophage Biosensor for Highly Sensitive and Specific Detection of Staphylococcus aureus | en_US |
dc.type | Article | en_US |
dc.relation.no | 39 | - |
dc.relation.volume | 9 | - |
dc.identifier.doi | 10.1021/acsami.7b07818 | - |
dc.relation.page | 33589-33598 | - |
dc.relation.journal | ACS APPLIED MATERIALS & INTERFACES | - |
dc.contributor.googleauthor | Bhardwaj, Neha | - |
dc.contributor.googleauthor | Bhardwaj, Sanjeev K. | - |
dc.contributor.googleauthor | Mehta, Jyotsana | - |
dc.contributor.googleauthor | Kim, Ki-Hyun | - |
dc.contributor.googleauthor | Deep, Akash | - |
dc.relation.code | 2017001478 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF ENGINEERING[S] | - |
dc.sector.department | DEPARTMENT OF CIVIL AND ENVIRONMENTAL ENGINEERING | - |
dc.identifier.pid | kkim61 | - |
dc.identifier.researcherID | I-8499-2018 | - |
dc.identifier.orcid | https://orcid.org/0000-0003-0487-4242 | - |
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