Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김기현 | - |
dc.date.accessioned | 2019-11-24T18:45:30Z | - |
dc.date.available | 2019-11-24T18:45:30Z | - |
dc.date.issued | 2017-04 | - |
dc.identifier.citation | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, v. 97, page. 616-624 | en_US |
dc.identifier.issn | 0141-8130 | - |
dc.identifier.issn | 1879-0003 | - |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0141813016310327?via%3Dihub | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/113848 | - |
dc.description.abstract | Accelerated use of pesticides in cutting edge agriculture prompted us to explore smart nanoformulations to subside the consumption of these perilous chemicals. Polymer nanocapsules carrying a fungicide, hexaconazole were developed through ionotropic gelation method utilizing chitosan and tripolyphosphate (TPP). The nanocapsules were characterized by photon correlation spectroscope (PCS), transmission electron microscope (TEM), and Fourier transform infra-red (FTIR) spectroscope. Nanocapsules were optimized for size and high encapsulation efficiency using central composite design (CCD) software. The encapsulation efficiency of nanocapsules for hexaconazole was 73% as assessed by gas chromatography (GC). Nanocapsules were analysed and compared with commercial formulation for controlled release in vitro at three different pH values. Release of hexaconazole from nanocapsules was fastest at pH 4 in comparison to pH 7 and pH 10. Release study in soil was also conducted and revealed a controlled pattern for nanoformulation. The fungicidal activity of the prepared nanoformulation was evaluated against R. solani and was compared with commercial formulation of hexaconazole. The cytotoxicity assay performed on vero cell lines by MTT(3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide) assay confirmed that nanoformulation is less toxic than commercial formulation of pesticide. (C) 2016 Elsevier B.V. All rights reserved. | en_US |
dc.description.sponsorship | Neetu Chauhan thanks CSIR for a fellowship in the form of a senior research fellowship (SRF). The authors are also thankful to Nano Mission, DST for providing research facilities and Director NRCE, Hisar for providing cell lines. The authors thank Dr. Jasbir Singh, IARI, for providing the TEM facility and Dr. Robin Gogoi, IARI, for helping assess in vitro antifungal activity. KHK also acknowledges partial support from a National Research Foundation of Korea (NRF) grant funded by the Ministry of Education, Science, and Technology (MEST) (No. 2009-0093848). | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | ELSEVIER SCIENCE BV | en_US |
dc.subject | Nanotechnology | en_US |
dc.subject | Chitosan | en_US |
dc.subject | Hexaconazole | en_US |
dc.subject | Controlled release | en_US |
dc.subject | lonotropic gelation | en_US |
dc.subject | Fungicide | en_US |
dc.title | Development of chitosan nanocapsules for the controlled release of hexaconazole | en_US |
dc.type | Article | en_US |
dc.relation.volume | 97 | - |
dc.identifier.doi | 10.1016/j.ijbiomac.2016.12.059 | - |
dc.relation.page | 616-624 | - |
dc.relation.journal | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | - |
dc.contributor.googleauthor | Chauhan, Neetu | - |
dc.contributor.googleauthor | Dilbaghi, Neeraj | - |
dc.contributor.googleauthor | Gopal, Madhuban | - |
dc.contributor.googleauthor | Kumar, Rajesh | - |
dc.contributor.googleauthor | Kim, Ki-Hyun | - |
dc.contributor.googleauthor | Kumar, Sandeep | - |
dc.relation.code | 2017001181 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF ENGINEERING[S] | - |
dc.sector.department | DEPARTMENT OF CIVIL AND ENVIRONMENTAL ENGINEERING | - |
dc.identifier.pid | kkim61 | - |
dc.identifier.researcherID | I-8499-2018 | - |
dc.identifier.orcid | http://orcid.org/0000-0003-0487-4242 | - |
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