Quantum Dot-Based Molecularly Imprinted Polymers on Three-Dimensional Origami Paper Microfluidic Chip for Fluorescence Detection of Phycocyanin
- Title
- Quantum Dot-Based Molecularly Imprinted Polymers on Three-Dimensional Origami Paper Microfluidic Chip for Fluorescence Detection of Phycocyanin
- Author
- 주재범
- Keywords
- paper-based microfluidic devices; molecularly imprinted polymers (MIPs); quantum dot; phycocyanin; fluorescence
- Issue Date
- 2017-02
- Publisher
- AMER CHEMICAL SOC
- Citation
- ACS SENSORS, v. 2, no. 2, page. 243-250
- Abstract
- In this work, we developed a novel strategy using fluorescent quantum dots (QDs) combined with molecularly imprinted polymers (MIPs) on three-dimensional (3D) origami paper-based microfluidic devices for specific recognition and sensitive detection of phycocyanin. This method can realize the liquid phase of QDs@MIPs being transferred to the solid-phase paper base and achieve easy portability for the analysis. Under optimal conditions, we successfully demonstrated the proposed paper@QDs@MIP5 3D microfluidic chip for the sensitive and selective detection of phycocyanin protein target in a simple and robust manner. Our results revealed that the method exhibited a dynamic response to phycocyanin in the range of 10-50 mg/L with a limit of detection of 2 mg/L. Importantly, this device could provide quantitative information very conveniently and show great potential to be further extended to the detection of other proteins or biomarkers for environmental and food safety research.
- URI
- https://pubs.acs.org/doi/10.1021/acssensors.6b00664https://repository.hanyang.ac.kr/handle/20.500.11754/112699
- ISSN
- 2379-3694
- DOI
- 10.1021/acssensors.6b00664
- Appears in Collections:
- GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
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