Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김종호 | - |
dc.date.accessioned | 2019-05-22T06:17:40Z | - |
dc.date.available | 2019-05-22T06:17:40Z | - |
dc.date.issued | 2018-05 | - |
dc.identifier.citation | ADVANCED HEALTHCARE MATERIALS, v. 7, No. 14, Page. 1701496 | en_US |
dc.identifier.issn | 2192-2640 | - |
dc.identifier.uri | https://onlinelibrary.wiley.com/doi/full/10.1002/adhm.201701496 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/105499 | - |
dc.description.abstract | It is required to exfoliate and functionalize 2D transition metal dichalcogenides (TMDs) in an aqueous solution for biological and medical applications. Herein, the approach for the simultaneous exfoliation and functionalization of 2D WS2 nanosheets using boronic acid-modified poly(vinyl alcohol) (B-PVA) in an aqueous solution is reported, and the B-PVA-functionalized WS2 nanosheets (B-PVA-WS2) are exploited as a fluorescent biosensor for the detection of glycated hemoglobin, HbA1c. The synthetic B-PVA polymer facilitates the exfoliation and functionalization of WS2 nanosheets from the bulk counterpart in the aqueous solution via a pulsed sonication process, resulting in fluorescent B-PVA-WS2 nanohybrids with a specific recognition of HbA1c. The fluorescence of the B-PVA-WS2 is quenched in the presence of HbA1c, whereas PVA-functionalized WS2 (PVA-WS2), not bearing boronic acid as a recognition moiety, shows no fluorescence changes upon the addition of the target. The B-PVA-WS2 is able to selectively detect HbA1c at the concentration as low as 3.3 x 10(-8) m based on its specific fluorescence quenching. | en_US |
dc.description.sponsorship | J.-K.Y. and H.-R.L. contributed equally to this work. This work was supported by the Basic Science Research Program (2008-0061891, NRF-2014R1A2A1A11051877, and NRF-2017R1A2B2008455) through the National Research Foundation of Korea funded by the Ministry of Science and ICT. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | WILEY | en_US |
dc.subject | aqueous exfoliation | en_US |
dc.subject | fluorescent WS2 nanosheet | en_US |
dc.subject | HbA1c detection | en_US |
dc.subject | optical biosensors | en_US |
dc.subject | WS2 functionalization | en_US |
dc.title | Fluorescent 2D WS₂ Nanosheets Bearing Chemical Affinity Elements for the Recognition of Glycated Hemoglobin | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1002/adhm.201701496 | - |
dc.relation.page | 1-6 | - |
dc.relation.journal | ADVANCED HEALTHCARE MATERIALS | - |
dc.contributor.googleauthor | Yang, Jin‐Kyoung | - |
dc.contributor.googleauthor | Lee, Hye‐Rim | - |
dc.contributor.googleauthor | Hwang, In‐Jun | - |
dc.contributor.googleauthor | Kim, Hye‐In | - |
dc.contributor.googleauthor | Yim, DaBin | - |
dc.contributor.googleauthor | Kim, Jong‐Ho | - |
dc.relation.code | 2018003991 | - |
dc.sector.campus | E | - |
dc.sector.daehak | COLLEGE OF ENGINEERING SCIENCES[E] | - |
dc.sector.department | DEPARTMENT OF MATERIALS SCIENCE AND CHEMICAL ENGINEERING | - |
dc.identifier.pid | kjh75 | - |
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