Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김종호 | - |
dc.date.accessioned | 2019-05-14T07:10:21Z | - |
dc.date.available | 2019-05-14T07:10:21Z | - |
dc.date.issued | 2009-12 | - |
dc.identifier.citation | SMALL , v. 6, No 1, Page. 119-125 | en_US |
dc.identifier.issn | 1613-6810 | - |
dc.identifier.uri | https://onlinelibrary.wiley.com/doi/full/10.1002/smll.200901459 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/104232 | - |
dc.description.abstract | In this study, surface-enhanced Raman spectroscopy (SERS)-encoded magnetic nanoparticles (NPs) are prepared and utilized as a multifunctional tagging material for cancer-cell targeting and separation. First, silver-embedded magnetic NPs are prepared, composed of an 18-nm magnetic core and a 16-nm-thick silica shell with silver NPs formed on the surface. After simple aromatic compounds are adsorbed on the silver-embedded magnetic NPs, they are coated with. silica to provide them with chemical and physical stability. The resulting silica-encapsulated magnetic NPs (M-SERS dots) produce strong SERS signals and have magnetic properties. In a model application as a tagging material, the M-SERS dots are successfully utilized for targeting breast-cancer cells (SKBR3) and floating leukemia cells (SP2/O). The targeted cancer cells can be easily separated from the untargeted cells using an external magnetic field. The separated targeted cancer cells exhibit a Raman signal originating from the M-SERS dots. This system proves to be an efficient tool for separating targeted cells. Additionally, the magnetic-field-induced hot spots, which can provide a 1000-times-stronger SERS intensity due to aggregation of the NPs, are studied. | en_US |
dc.description.sponsorship | This work was supported by the Nano-Systems Institute (NSI-NCRC) program and the Brain Korea 21 Program supported by the Ministry of Education and Human Resources Development. T.H. acknowledges financial support provided by the Korean Ministry of Science and Technology through the National Creative Research Initiative Program of the Korea Science and Engineering Foundation (KOSEF). | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | WILEY-V C H VERLAG GMBH | en_US |
dc.subject | magnetic materials | en_US |
dc.subject | optically active materials | en_US |
dc.subject | silver nanoparticles | en_US |
dc.subject | surface-enhanced Raman scattering | en_US |
dc.title | Multifunctional silver embedded magnetic nanoparticles as SERS nanoprobe and their applications | en_US |
dc.type | Article | en_US |
dc.relation.volume | 237 | - |
dc.identifier.doi | 10.1002/smll.200901459 | - |
dc.relation.page | 241-241 | - |
dc.relation.journal | SMALL | - |
dc.contributor.googleauthor | Jun, Bong-Hyun | - |
dc.contributor.googleauthor | Noh, Misuk | - |
dc.contributor.googleauthor | Kim, Jaeyun | - |
dc.contributor.googleauthor | Kim, Gunsung | - |
dc.contributor.googleauthor | Kang, Homan | - |
dc.contributor.googleauthor | Seo, Young-Tae | - |
dc.contributor.googleauthor | Baek, Jongho | - |
dc.contributor.googleauthor | Kim, Jong-Ho | - |
dc.contributor.googleauthor | Park, Juyoung | - |
dc.contributor.googleauthor | Kim, Seongyong | - |
dc.contributor.googleauthor | Kim, Yong-Kweon | - |
dc.contributor.googleauthor | Hyeon, Taeghwan | - |
dc.contributor.googleauthor | Cho, Myung-Haing | - |
dc.contributor.googleauthor | Jeong, Dae Hong | - |
dc.contributor.googleauthor | Lee, Yoon Sik | - |
dc.relation.code | 2009216616 | - |
dc.sector.campus | E | - |
dc.sector.daehak | COLLEGE OF ENGINEERING SCIENCES[E] | - |
dc.sector.department | DEPARTMENT OF MATERIALS SCIENCE AND CHEMICAL ENGINEERING | - |
dc.identifier.pid | kjh75 | - |
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