A Randomized Controlled Trial of Compression Rates during Cardiopulmonary Resuscitation
- Title
- A Randomized Controlled Trial of Compression Rates during Cardiopulmonary Resuscitation
- Author
- 강형구
- Keywords
- Cardiopulmonary Resuscitation; Cardiac Arrest; Basic Life Support
- Issue Date
- 2016-08
- Publisher
- KOREAN ACAD MEDICAL SCIENCES
- Citation
- JOURNAL OF KOREAN MEDICAL SCIENCE, v. 31, NO. 9, Page. 1491-1491
- Abstract
- The objective of this study was to compare the efficacy of cardiopulmonary resuscitation (CPR) with 120 compressions per minute (CPM) to CPR with 100 CPM in patients with nontraumatic out-of-hospital cardiac arrest. We randomly assigned patients with nontraumatic out-of-hospital cardiac arrest into two groups upon arrival to the emergency department (ED). The patients received manual CPR either with 100 CPM (CPR-100 group) or 120 CPM (CPR-120 group). The primary outcome measure was sustained restoration of spontaneous circulation (ROSC). The secondary outcome measures were survival discharge from the hospital, one-month survival, and one-month survival with good functional status. Of 470 patients with cardiac arrest, 136 patients in the CPR-100 group and 156 patients in the CPR-120 group were included in the final analysis. A total of 69 patients (50.7%) in the CPR-100 group and 67 patients (42.9%) in the CPR-120 group had ROSC (absolute difference, 7.8% points; 95% confidence interval [CI], -3.7 to 19.2%; P = 0.183). The rates of survival discharge from the hospital, one-month survival, and one-month survival with good functional status were not different between the two groups (16.9% vs. 12.8%, P = 0.325; 12.5% vs. 6.4%, P = 0.073; 5.9% vs. 2.6%, P = 0.154, respectively). We did not find differences in the resuscitation outcomes between those who received CPR with 100 CPM and those with 120 CPM. However, a large trial is warranted, with adequate power to confirm a statistically non-significant trend toward superiority of CPR with 100 CPM. (Clinical Trial Registration Information: www.cris.nih.go.kr, cris.nih.go.kr number, KCT0000231)
- URI
- https://synapse.koreamed.org/DOIx.php?id=10.3346/jkms.2016.31.9.1491https://repository.hanyang.ac.kr/handle/20.500.11754/76381
- ISSN
- 1011-8934; 1598-6357
- DOI
- 10.3346/jkms.2016.31.9.1491
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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