Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 심재항 | - |
dc.date.accessioned | 2018-04-19T23:25:50Z | - |
dc.date.available | 2018-04-19T23:25:50Z | - |
dc.date.issued | 2011-08 | - |
dc.identifier.citation | Journal of Clinical Anesthesia, 2011, 23(5), P.379-383 | en_US |
dc.identifier.issn | 0952-8180 | - |
dc.identifier.uri | http://www.sciencedirect.com/science/article/pii/S0952818011002005?via%3Dihub | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/70010 | - |
dc.description.abstract | Study Objective: To determine the most suitable effect-site concentration of remifentanil during lightwand intubation when administered with a target-controlled infusion (TCI) of propofol at 4.0 mu g/mL without neuromuscular blockade.Design: Prospective study using a modified Dixon's up-and-down method.Setting: Operating room of an academic hospital.Patients: 28 ASA physical status 1 and 2 patients, aged 18-65 years, scheduled for minor elective surgery.Interventions: Anesthesia was induced by TCI propofol effect-site concentration to 4.0 mu g/mL, and the dose of remifentanil given to each patient was determined by the response of the previously tested patient using 0.2 ng/mL as a step size. The first patient was tested at a target effect-site concentration of 4.0 ng/mL of remifentanil. If intubation was successful, the remifentanil dose was decreased by 0.2 ng/mL; if it failed, the remifentanil close was increased by 0.2 ng/mL. Successful intubation was defined as excellent or good intubating conditions.Measurements and Main Results: The remifentanil effect-site concentration was measured. The optimal effect-site concentration of remifentanil for lightwand tracheal intubation during propofol induction using 2% propofol target effect-site concentration to 4 mu g/mL was 2.16 +/- 0.19 ng/mL. From probit analysis, the effect-site concentration of remifentanil required for successful lightwand intubation in 50% (EC50) and 95% (EC95) of adults was 2.11 ng/mL (95% CI 1.16-2.37 ng/mL) and 2.44 ng/mL (95% Cl 2.20-3.79 ng/mL), respectively.Conclusion: A remifentanil effect-site concentration of 2.16 +/- 0.19 ng/mL given before a propofol effect-site concentration of 4 mu g/mL allowed lightwand intubation without muscle relaxant. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Elsevier Science INC | en_US |
dc.subject | Equipment and supplies | en_US |
dc.subject | Lightwand | en_US |
dc.subject | Intubation | en_US |
dc.subject | Intratracheal | en_US |
dc.subject | Remifentanil | en_US |
dc.subject | Effect-site concentrations | en_US |
dc.title | The optimal effect-site concentration of remifentanil for lightwand tracheal intubation during propofol induction without muscle relaxation | en_US |
dc.type | Article | en_US |
dc.relation.no | 5 | - |
dc.relation.volume | 23 | - |
dc.identifier.doi | 10.1016/j.jclinane.2010.12.012 | - |
dc.relation.page | 379-383 | - |
dc.relation.journal | JOURNAL OF CLINICAL ANESTHESIA | - |
dc.contributor.googleauthor | Han, Jeong Uk | - |
dc.contributor.googleauthor | Cho, Sangyun | - |
dc.contributor.googleauthor | Jeon, Woo Jae | - |
dc.contributor.googleauthor | Yeom, Jong Hoon | - |
dc.contributor.googleauthor | Shin, Woo Jong | - |
dc.contributor.googleauthor | Shim, Jae Hang | - |
dc.contributor.googleauthor | Kim, Kyoung Hun | - |
dc.relation.code | 2011204832 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | jhshim | - |
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