Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 이기정 | - |
dc.date.accessioned | 2018-04-16T02:20:43Z | - |
dc.date.available | 2018-04-16T02:20:43Z | - |
dc.date.issued | 2012-03 | - |
dc.identifier.citation | BIOCONJUGATE CHEMISTRY, Vol.23, No.3 [2012], p350-362 | en_US |
dc.identifier.issn | 1043-1802 | - |
dc.identifier.uri | https://pubs.acs.org/doi/10.1021/bc200232d | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/67492 | - |
dc.description.abstract | Novel vinylsulfone cyanine dyes (em. 550-850 nm) were designed and synthesized for fluorescent labeling of biomolecules via 1,2-addition reaction in aqueous conditions. Due to the virtue of chemical structures of both fluorophore and reactive group, these dyes could be significantly stable and reactive in various aqueous/organic conditions. A wide variety of pH, temperature, buffer concentration, and protein were tested for the optimal labeling condition. | en_US |
dc.description.sponsorship | This work was supported by the project No. 10033024 from the Advanced Technology Center (ATC) Support Program of Ministry of Knowledge Economy (Republic of Korea). We thank Kinam Park, Ph.D. (Professor of Pharmaceutics, Purdue University) for support in dye conjugation ratio measurements, Sang Yeul Lee, Ph.D. (Sogang University), and Namho Kim (BioActs Co. Ltd.). The three novel cyanine compounds (7g, 7l, and 7n) are available by BioActs Co. Ltd (Code No. PWA1119, PWA1215, and PWA1308). | en_US |
dc.language.iso | en | en_US |
dc.publisher | ACS AMERICAN CHEMICAL SOCIETY | en_US |
dc.subject | N-HYDROXYSUCCINIMIDE ESTERS | en_US |
dc.subject | REAGENTS | en_US |
dc.subject | KINETICS | en_US |
dc.subject | PROBES | en_US |
dc.subject | DNA | en_US |
dc.title | Novel Cyanine Dyes with Vinylsulfone Group for Labeling Biomolecules | en_US |
dc.type | Article | en_US |
dc.relation.volume | 23 | - |
dc.identifier.doi | 10.1021/bc200232d | - |
dc.relation.page | 350-362 | - |
dc.relation.journal | BIOCONJUGATE CHEMISTRY | - |
dc.contributor.googleauthor | Park, J.W. | - |
dc.contributor.googleauthor | Kim, Y. | - |
dc.contributor.googleauthor | Lee, K.-J. | - |
dc.contributor.googleauthor | Kim, D.J. | - |
dc.relation.code | 2012201260 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF ENGINEERING[S] | - |
dc.sector.department | DEPARTMENT OF CHEMICAL ENGINEERING | - |
dc.identifier.pid | leekj | - |
dc.identifier.researcherID | 15132227000 | - |
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