Semiautomated spleen volumetry with diffusion-weighted MR imaging

Abstract

In this article, we determined the relative accuracy of semiautomated spleen volumetry with diffusion‐weighted (DW) MR images compared to standard manual volumetry with DW‐MR or CT images. Semiautomated spleen volumetry using simple thresholding followed by 3D and 2D connected component analysis was performed with DW‐MR images. Manual spleen volumetry was performed on DW‐MR and CT images. In this study, 35 potential live liver donor candidates were included. Semiautomated volumetry results were highly correlated with manual volumetry results using DW‐MR (r = 0.99; P < 0.0001; mean percentage absolute difference, 1.43 ± 0.94) and CT (r = 0.99; P < 0.0001; 1.76 ± 1.07). Mean total processing time for semiautomated volumetry was significantly shorter compared to that of manual volumetry with DW‐MR (P < 0.0001) and CT (P < 0.0001). In conclusion, semiautomated spleen volumetry with DW‐MR images can be performed rapidly and accurately when compared with standard manual volumetry. Magn Reson Med, 2012. © 2011 Wiley Periodicals, Inc.