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Bilateral Acute Renal Cortical Necrosis in SLE-Associated Antiphospholipid Syndrome

Title
Bilateral Acute Renal Cortical Necrosis in SLE-Associated Antiphospholipid Syndrome
Author
김근호
Keywords
Antiphospholipid syndrome; kidney cortex necrosis; lupus erythematosus; systemic
Issue Date
2011-06
Publisher
W B SAUNDERS CO
Citation
American Journal of Kidney Diseases, 2011, 57(6), P.945-947
Abstract
Acute renal cortical necrosis (ARCN) is a rare cause of acute kidney injury and is characterized by the entire destruction of the renal cortex. We describe a 16-year-old girl with unremarkable personal or family history who presented with acute anuria and dyspnea. Evaluation showed acute kidney injury associated with metabolic acidosis, hyperkalemia, anemia, thrombocytopenia, hematuria, and proteinuria. Serologic tests showed systemic lupus erythematosus-related antiphospholipid syndrome with low serum complement C3 levels, positive anti-double-stranded DNA antibody, positive antiphospholipid antibody, and positive antinuclear antibody. Contrast-enhanced abdominal computed tomography confirmed the presence of ARCN by showing contrasted medulla and a thin layer of subcapsular cortex, but without bilateral enhancement of the renal cortex. This case shows the role of imaging in patients with bilateral ARCN in systemic lupus erythematosus-related antiphospholipid syndrome.
URI
http://www.ajkd.org/article/S0272-6386(11)00620-2/fulltexthttp://hdl.handle.net/20.500.11754/66687
ISSN
0272-6386
DOI
10.1053/j.ajkd.2011.02.381
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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