72 54

Bio-inspired Hybrid Carbon Nanotube Muscles

Title
Bio-inspired Hybrid Carbon Nanotube Muscles
Author
김선정
Keywords
CELL-BASED ACTUATORS; SKELETAL-MUSCLE; MYOBLAST DIFFERENTIATION; BIOLOGICAL MACHINES; THIN-FILMS; HIGH-POWER; SCAFFOLDS; GRAPHENE; STIMULATION; FABRICATION
Issue Date
2016-05
Publisher
NATURE PUBLISHING GROUP
Citation
SCIENTIFIC REPORTS, v. 6, Page. 1-8
Abstract
There has been continuous progress in the development for biomedical engineering systems of hybrid muscle generated by combining skeletal muscle and artificial structure. The main factor affecting the actuation performance of hybrid muscle relies on the compatibility between living cells and their muscle scaffolds during cell culture. Here, we developed a hybrid muscle powered by C2C12 skeletal muscle cells based on the functionalized multi-walled carbon nanotubes (MWCNT) sheets coated with poly(3,4-ethylenedioxythiophene) (PEDOT) to achieve biomimetic actuation. This hydrophilic hybrid muscle is physically durable in solution and responds to electric field stimulation with flexible movement. Furthermore, the biomimetic actuation when controlled by electric field stimulation results in movement similar to that of the hornworm by patterned cell culture method. The contraction and relaxation behavior of the PEDOT/MWCNT-based hybrid muscle is similar to that of the single myotube movement, but has faster relaxation kinetics because of the shape-maintenance properties of the freestanding PEDOT/MWCNT sheets in solution. Our development provides the potential possibility for substantial innovation in the next generation of cell-based biohybrid microsystems.
URI
https://www.nature.com/articles/srep26687http://hdl.handle.net/20.500.11754/65842
ISSN
2045-2322
DOI
10.1038/srep26687
Appears in Collections:
COLLEGE OF ENGINEERING[S](공과대학) > ELECTRICAL AND BIOMEDICAL ENGINEERING(전기·생체공학부) > Articles
Files in This Item:
Bio-inspired Hybrid Carbon Nanotube Muscles.pdfDownload
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE