Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박병배 | - |
dc.date.accessioned | 2018-03-30T06:44:04Z | - |
dc.date.available | 2018-03-30T06:44:04Z | - |
dc.date.issued | 2012-12 | - |
dc.identifier.citation | Acta Haematologica, 2014, 127(2), P.100~104 | en_US |
dc.identifier.issn | 0001-5792 | - |
dc.identifier.issn | 1421-9662 | - |
dc.identifier.uri | https://www.karger.com/Article/Abstract/333113 | - |
dc.description.abstract | Purpose: Primary thyroid marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue type (pTY-MZL) is an extremely uncommon form of lymphoma. Due to its rarity, the natural history and optimal treatment modality for this disease have yet to be clearly established. Methods: A total of 27 patients with histologically confirmed pTY-MZL were retrospectively analyzed. Results: The median age of our subjects was 53 years (range 25?82). This study involved 17 females (63.0%) and 10 males (37.0%). Twenty-four out of 27 patients (88.9%) initially presented with localized disease, defined by Ann Arbor stage I/II. Bone marrow involvement was detected in 8.3% of the patients (2 patients), and 91.7% of the patients (25 of 27) were categorized into the low or low-intermediate risk group, according to the International Prognostic Index criteria. Accompanying Hashimoto’s thyroiditis was detected in 72% of the patients, whereas thyroglobulin antibody levels were elevated in 70% of the patients. Twenty-six patients were treated with surgery, radiotherapy or chemotherapy, and 25 patients achieved complete remission. During the follow-up period, only 2 patients evidenced progression, and no deaths occurred over the course of the study. Conclusion: pTY-MZL tends to be an indolent disease. However, unlike other mucosa-associated lymphoid tissue site MZLs, pTY-MZL was well controlled via several treatment modalities, and the patients’ responses were sustained for a prolonged period. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Instytut Matematyczny | en_US |
dc.subject | B-cell lymphoma | en_US |
dc.subject | Marginal zone | en_US |
dc.subject | Thyroid | en_US |
dc.title | Primary Thyroid Marginal Zone B-Cell Lymphoma of the Mucosa-Associated Lymphoid Tissue Type: Clinical Manifestation and Outcome of a Rare Disease - Consortium for Improving Survival of Lymphoma Study | en_US |
dc.type | Article | en_US |
dc.relation.no | 2 | - |
dc.relation.volume | 127 | - |
dc.identifier.doi | 10.1159/000333113 | - |
dc.relation.page | 100-104 | - |
dc.relation.journal | ACTA HAEMATOLOGICA | - |
dc.relation.code | 2012200086 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | bbpark | - |
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