Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박진규 | - |
dc.date.accessioned | 2018-03-26T07:59:12Z | - |
dc.date.available | 2018-03-26T07:59:12Z | - |
dc.date.issued | 2014-12 | - |
dc.identifier.citation | EUROPACE, 2014, 16(12), p.1738-1745 | en_US |
dc.identifier.issn | 1099-5129 | - |
dc.identifier.issn | 1532-2092 | - |
dc.identifier.uri | https://academic.oup.com/europace/article/16/12/1738/490994 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/52586 | - |
dc.description.abstract | Aims Although circumferential pulmonary vein isolation (CPVI) has been considered as the cornerstone for paroxysmal atrial fibrillation (PAF) ablation, there has been a substantial recurrence rate. We conducted a prospectively randomized study to evaluate whether additional linear ablation from the superior vena cava (SVC) to the right atrial (RA) septum (SVC-L) improves the clinical outcome.Methods and results This study enroled 200 patients with PAF (male 74.5%, 56.8 +/- 11.7 years old) randomly assigned to either the CPVI (n = 100) or CPVI +/- SVC-L (n = 100) groups. An RA isthmus ablation was performed in all patients. The CPVI +/- SVC-L group required a longer ablation procedure time (82.7 +/- 17.9 min) than the CPVI group (63.6 +/- 16.8 min, P < 0.001). The complication rates were 5% in CPVI +/- SVC-L group and 2% in CPVI group, < respectively (P = 0.445). Two CPVI +/- SVC-L group patients had post-procedural sinus node dysfunction, which recovered within 24 h. During 12.2 +/- 5.3 months of follow-uP < the recurrence rate was significantly lower in the CPVI +/- SVC-L group (6%) than the CPVI group (27%, P < 0.001). The post-procedural 3-month follow-up heart rate variability in the CPVI +/- SVC-L group showed a significantly greater reduction in the rMSSD (25.2 +/- 13.7 vs. 13.7 +/- 8.5 ms, P < 0.001), HF (10.2 +/- 7.1 vs. 5.5 +/- 5.8 ms(2), P < 0.001), and LF/HF (1.6 +/- 0.5 vs. 0.9 +/- 0.3, P < 0.001) than in the CPVI group.Conclusion In spite of a longer procedure time and risk of transient sinus node dysfunction, an SVC-L in addition to CPVI improved the clinical outcome of catheter ablation, and was associated with post-procedural autonomic neural remodelling in patients with PAF. | en_US |
dc.description.sponsorship | This work was supported by a grant (A085136) from the Korea Health 21 R&D Project, Ministry of Health and Welfare, and a grant (7-2013-0362) from the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT & Future Planning (MSIP). | en_US |
dc.language.iso | en | en_US |
dc.publisher | OXFORD UNIV PRESS, GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND | en_US |
dc.subject | Paroxysmal atrial fibrillation | en_US |
dc.subject | Catheter ablation | en_US |
dc.subject | Superior vena cava | en_US |
dc.subject | Recurrence | en_US |
dc.subject | RADIOFREQUENCY CATHETER ABLATION | en_US |
dc.subject | HEART-RATE-VARIABILITY | en_US |
dc.subject | ELECTRICAL ISOLATION | en_US |
dc.subject | FOLLOW-UP | en_US |
dc.subject | MANAGEMENT | en_US |
dc.subject | SURGERY | en_US |
dc.subject | SYSTEM | en_US |
dc.subject | TRIAL | en_US |
dc.title | Additional linear ablation from the superior vena cava to right atrial septum after pulmonary vein isolation improves the clinical outcome in patients with paroxysmal atrial fibrillation: prospective randomized study | en_US |
dc.type | Article | en_US |
dc.relation.no | 12 | - |
dc.relation.volume | 16 | - |
dc.identifier.doi | 10.1093/europace/euu226 | - |
dc.relation.page | 1738-1745 | - |
dc.relation.journal | EUROPACE | - |
dc.contributor.googleauthor | Kang, Ki-Woon | - |
dc.contributor.googleauthor | Pak, Hui-Nam | - |
dc.contributor.googleauthor | Park, Junbeom | - |
dc.contributor.googleauthor | Park, Jin Gyu | - |
dc.contributor.googleauthor | Uhm, Jae Sun | - |
dc.contributor.googleauthor | Joung, Boyoung | - |
dc.contributor.googleauthor | Lee, Moon-Hyoung | - |
dc.contributor.googleauthor | Hwang, Chun | - |
dc.relation.code | 2014029149 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | cardiohy | - |
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