할로페리돌과 아리피프라졸을 복용하는 조현병 환자에서의 운전능력 관련 정신운동수행
- Title
- 할로페리돌과 아리피프라졸을 복용하는 조현병 환자에서의 운전능력 관련 정신운동수행
- Other Titles
- Psychomotor Performance Relevant to Driving Ability in Patients with Schizophrenia Treated with Haloperidol and Aripiprazole
- Author
- 노성원
- Keywords
- 조현병; 할로페리돌; 아리피프라졸; 운전; 정신운동수행; Schizophrenia; Haloperidol; Aripiprazole; Driving; Psychomotor performance
- Issue Date
- 2012-09
- Publisher
- 대한조현병학회
- Citation
- 대한조현병학회지(Korean Journal of Schizophrenia Research), 2012, 15(2), P.99-105, 7P.
- Abstract
- Objectives : This study aimed to compare psychomotor performance related with automobile driving in patients with schizophrenia under the treatment of a typical antipsychotic agent, haloperidol, or an atypical antipsychotic agent, aripiprazole. Methods : We evaluated driving ability of schizophrenia patients by using the cognitive perceptual assessment for driving (CPAD). Twelve patients receiving haloperidol monotherapy and 18 taking aripiprazole monotherapy participated in this study and the results of CPAD were compared with each other. Results : Of 30 participants, 15 (50%) of the patients passed the CPAD to be regarded as competent to drive, 3 (10%) of the patients failed the CPAD considered to be severely impaired. Controlling for sex, age, education, duration of illness, there were no significant differences in the CPAD results between two treatment groups. We observed a trend that patients who received aripiprazole showed a higher total score of the CPAD than haloperidol-treated patients (55.2±4.9 vs. 45.7±8.4, p=0.080). Conclusion : There were no significant differences in the psychomotor performance relevant to driving ability between haloperidol and aripiprazole groups. But our results suggest that aripiprazole might have the neurocognitive advantage over haloperidol. Future study with a large sample size and diverse antipsychotics is warranted.
- URI
- https://synapse.koreamed.org/DOIx.php?id=10.16946/kjsr.2012.15.2.99http://hdl.handle.net/20.500.11754/50173
- ISSN
- 2287-6995
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
- Files in This Item:
There are no files associated with this item.
- Export
- RIS (EndNote)
- XLS (Excel)
- XML