Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김현영 | - |
dc.date.accessioned | 2018-03-21T07:12:53Z | - |
dc.date.available | 2018-03-21T07:12:53Z | - |
dc.date.issued | 2012-09 | - |
dc.identifier.citation | Archives of Neurology, Sep 2012, Nol.69,No.9, P.1193-1196 | en_US |
dc.identifier.issn | 0003-9942 | - |
dc.identifier.uri | http://jamanetwork.com.ssl.access.hanyang.ac.kr/journals/jamaneurology/fullarticle/1190811 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/50116 | - |
dc.description.abstract | OBJECTIVE: To describe the case of a patient who had been receiving adalimumab for rheumatoid arthritis and died of varicella-zoster virus vasculopathy with multifocal cerebral hemorrhage. DESIGN: Case report. SETTING: Hanyang University Hospital, Seoul, Republic of Korea. PATIENT: A 66-year-old woman with adalimumab therapy for rheumatoid arthritis followed by stuporous mental changes. RESULTS: Magnetic resonance imaging scans showed multifocal parenchymal lesions and hemorrhage in the brainstem and supratentorial areas. Polymerase chain reaction analysis of the cerebrospinal fluid was positive for varicella-zoster virus. The patient died of multifocal vasculopathy despite intensive antiviral and antibacterial medication. CONCLUSIONS: Varicella-zoster virus multifocal vasculopathy with encephalitis may be associated with adalimumab therapy. Clinicians should be aware of the possibility of fatal varicella-zoster virus vasculopathy with encephalitis in patients undergoing adalimumab therapy for rheumatoid arthritis. | en_US |
dc.language.iso | en | en_US |
dc.publisher | American Medical Association | en_US |
dc.subject | Aged | en_US |
dc.subject | Antibodies | en_US |
dc.subject | Monoclonal | en_US |
dc.subject | Humanized | en_US |
dc.subject | adverse effects | en_US |
dc.subject | therapeutic use | en_US |
dc.subject | Antirheumatic Agents | en_US |
dc.subject | Arthritis | en_US |
dc.subject | Rheumatoid | en_US |
dc.subject | drug therapy | en_US |
dc.subject | Encephalitis | en_US |
dc.subject | Varicella Zoster | en_US |
dc.subject | chemically induced | en_US |
dc.subject | virology | en_US |
dc.subject | Fatal Outcome | en_US |
dc.subject | Female | en_US |
dc.subject | Herpesvirus 3 | en_US |
dc.subject | Human | en_US |
dc.subject | Humans | en_US |
dc.subject | Vasculitis | en_US |
dc.subject | Central Nervous System | en_US |
dc.title | Fatal Varicella-Zoster Virus Vasculopathy Associated With Adalimumab Therapy | en_US |
dc.type | Article | en_US |
dc.relation.no | 9 | - |
dc.relation.volume | 69 | - |
dc.identifier.doi | 10.1001/archneurol.2011.3741 | - |
dc.relation.page | 1193-1196 | - |
dc.relation.journal | ARCHIVES OF NEUROLOGY | - |
dc.contributor.googleauthor | Baek, Wonki | - |
dc.contributor.googleauthor | Lee, Sang-Gon | - |
dc.contributor.googleauthor | Kim, Young Seo | - |
dc.contributor.googleauthor | Kim, Jae-Hoon | - |
dc.contributor.googleauthor | Jun, Jae-Bum | - |
dc.contributor.googleauthor | Kim, Hyun Young | - |
dc.contributor.googleauthor | 백원기 | - |
dc.contributor.googleauthor | 이상곤 | - |
dc.contributor.googleauthor | 김영서 | - |
dc.contributor.googleauthor | 김재훈 | - |
dc.contributor.googleauthor | 전재범 | - |
dc.contributor.googleauthor | 김현영 | - |
dc.relation.code | 2012200962 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | hyoungkim1 | - |
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