Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김태환 | - |
dc.date.accessioned | 2018-03-06T06:12:53Z | - |
dc.date.available | 2018-03-06T06:12:53Z | - |
dc.date.issued | 2012-12 | - |
dc.identifier.citation | Annals of the rheumatic diseases,Vol.71,No.10 [2012],p1593-1595 | en_US |
dc.identifier.issn | 0003-4967 | - |
dc.identifier.uri | http://search.proquest.com/docview/1778067035?accountid=11283 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/42932 | - |
dc.description.abstract | a subsequent study hinted at a possible increase in risk of fractures in NSAID users despite an increase in BMD. 9 Analysis of the Canadian Multicentre Osteoporosis Study on the effects of NSAIDs on BMD led to interesting findings. 10 The use of NSAIDs was associated with a decrease in BMD in men and increase in postmenopausal women who did not receive oestrogen replacement. 10 The authors concluded that the effect of NSAIDs seen in this study is a reflection of suppression of inflammation associated with the postmenopausal state, while the direct effect of prostaglandin inhibition on bone is manifest in men as a decrease in BMD. [...]there are few studies to inform the decision on whether NSAIDs should be continued when a biological agent is administered, although our recent experience provides supportive evidence for this approach. 4 Both for the pivotal phase 3 random control trials of biological agents in AS and current third-party coverage, inadequate control of symptoms by NSAIDs has become the criteria for use of anti-TNF agents. [...]the published literature on the effects of anti-TNF agents on bone formation is based largely on experience with NSAID non-responders. | en_US |
dc.language.iso | en | en_US |
dc.publisher | BMJ PUBLISHING GROUP | en_US |
dc.subject | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | en_US |
dc.subject | BONE-MINERAL DENSITY | en_US |
dc.subject | SYNDESMOPHYTE FORMATION | en_US |
dc.subject | PROSTAGLANDIN E-2 | en_US |
dc.subject | SPINAL-FUSION | en_US |
dc.subject | OLDER WOMEN | en_US |
dc.subject | SPONDYLOARTHRITIS | en_US |
dc.subject | RECOMMENDATIONS | en_US |
dc.subject | DICKKOPF-1 | en_US |
dc.subject | MANAGEMENT | en_US |
dc.title | NSAIDs and radiographic progression in ankylosing spondylitis | en_US |
dc.type | Article | en_US |
dc.relation.no | 10 | - |
dc.relation.volume | 71 | - |
dc.identifier.doi | 10.1136/annrheumdis-2012-201844 | - |
dc.relation.page | 1953-55 | - |
dc.relation.journal | ANNALS OF THE RHEUMATIC DISEASES | - |
dc.contributor.googleauthor | Haroon, Nigil | - |
dc.contributor.googleauthor | Kim, Tae-Hwan | - |
dc.contributor.googleauthor | Inman, Robert D | - |
dc.relation.code | 2012200731 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | thkim | - |
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