임상적으로 호전된 진행다초점백질뇌병증 환자의 백질 내 해부학적 연결성 추적관찰
- Title
- 임상적으로 호전된 진행다초점백질뇌병증 환자의 백질 내 해부학적 연결성 추적관찰
- Other Titles
- Serial Follow-up of White Matter Connectivity in a Patient with Progressive Multifocal Leukoencephalopathy Presenting Clinical Improvement
- Author
- 김승현
- Keywords
- Progressive multifocal leukoencephalopathy; Magnetic resonance spectroscopy; Tractography
- Issue Date
- 2011-05
- Publisher
- 대한신경과학회
- Citation
- 대한신경과학회지, 2011, vol.29, no.4, pp. 347-351 (5 pages)
- Abstract
- Progressive multifocal leukoencephalopathy (PML) is a fatal disease that is characterized by progressive demyelination of the cerebral white matter due to JC viral infection. We report serial magnetic resonance spectroscopy (MRS) and tractography changes in a patient with PML. After a three-cycle treatment with cidofovir and cytarabine, the patient exhibited remarkable improvements in motor and cognitive functions. Follow-up MRS and tractography revealed regeneration of the white-matter fibers. This is the first consecutive neuroimaging study showing improvements in neurological symptoms using MRS and tractography.
- URI
- https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART001600256
- ISSN
- 1225-7044
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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