A fatal case of hepatitis B virus (HBV) reactivation during long-term, very-low-dose steroid treatment in an inactive HBV carrier
- Title
- A fatal case of hepatitis B virus (HBV) reactivation during long-term, very-low-dose steroid treatment in an inactive HBV carrier
- Author
- 전용철
- Keywords
- Hepatitis B virus; Liver failure; Steroids; Virus activation
- Issue Date
- 2012-06
- Publisher
- Korean Association for The Study of Liver
- Citation
- Clinical and Molecular Hepatology, 2012, 18(2), P.225-228
- Abstract
- Hepatitis B virus (HBV) may be reactivated after chemotherapy or immunosuppressive therapy, and therefore administration of antiviral agents before such treatment is recommended. Most reported cases of reactivation are associated with high doses of immunosuppressive agents or combination therapy. We present a case of a previously inactive HBV carrier with an acute severe flare-up during a long-term, very-low-dose (2.5 mg/day) steroid treatment for rheumatoid arthritis. We suggest that even a minimal dose of single-regimen oral steroid can cause reactivation of indolent, inactive HBV.
- URI
- https://www.e-cmh.org/journal/view.php?doi=10.3350/cmh.2012.18.2.225
- ISSN
- 2287-2728; 2287-285X
- DOI
- 10.3350/cmh.2012.18.2.225
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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