Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 엄지은 | - |
dc.date.accessioned | 2018-02-15T03:42:37Z | - |
dc.date.available | 2018-02-15T03:42:37Z | - |
dc.date.issued | 2011-05 | - |
dc.identifier.citation | ONCOLOGY, 80, 1-2, p21-p28 | en_US |
dc.identifier.issn | 0030-2414 | - |
dc.identifier.uri | https://www.karger.com/Article/Abstract/327222 | - |
dc.description.abstract | Objective: Pediatric-type sarcomas such as Ewing's sarcoma (EWS)/primitive neuroectodermal tumor family and rhabdomyosarcoma are relatively uncommon in adult patients. Optimal treatment strategies for this population and prognosis in adult patients compared with pediatric patients remain controversial. Methods: We retrospectively reviewed pediatric-type sarcoma patients older than 15 years at a single institution. Results: A total of 84 consecutive patients between 1995 and 2009 were identified at the Samsung Medical Center, Seoul, Korea. Median age was 30 years with a range of 15-74 years. Forty-seven patients (56.0%) were diagnosed with Ewing's sarcoma/primitive neuroectodermal tumor family, 34 (40.5%) with rhabdomyosarcoma and 3 (3.6%) with desmoplastic round-cell tumor. Median follow-up duration was 5.9 years. Median overall survival for all patients was 33.1 months (95% CI 13.5-52.7) and median event-free survival for all patients was 14.4 months (95% CI 5.9-22.9 months). Multivariate analysis revealed that localized disease was a significant independent prognostic factor for longer overall survival (hazard ratio 0.30, 95% CI 0.14-0.66, p = 0.003), and favorable primary tumor sites were associated with longer event-free survival (hazard ratio 0.33, 95% CI 0.11-0.98, p = 0.045). Conclusion: We identified the prognostic variables which may facilitate risk-adapted therapies for this rare adult sarcoma group, which should be further investigated. Copyright (C) 2011 S. Karger AG, Basel | en_US |
dc.language.iso | en | en_US |
dc.publisher | KARGER | en_US |
dc.subject | Pediatric-type sarcoma | en_US |
dc.subject | Rhabdomyosarcoma | en_US |
dc.subject | Ewing's sarcoma | en_US |
dc.subject | Primitive neuroectodermal tumor family | en_US |
dc.subject | Desmoplastic small round-cell tumor | en_US |
dc.subject | Prognosis | en_US |
dc.title | Analysis of Prognostic Factors of Pediatric-Type Sarcomas in Adult Patients | en_US |
dc.type | Article | en_US |
dc.relation.no | 1-2 | - |
dc.relation.volume | 80 | - |
dc.identifier.doi | 10.1159/000327222 | - |
dc.relation.page | 21-28 | - |
dc.relation.journal | ONCOLOGY | - |
dc.contributor.googleauthor | Lee, Jee Yun | - |
dc.contributor.googleauthor | Lee, Jeeyun | - |
dc.contributor.googleauthor | Ahn, Hee Kyung | - |
dc.contributor.googleauthor | Uhm, Ji Eun | - |
dc.contributor.googleauthor | Lee, Jeeyun | - |
dc.contributor.googleauthor | Lee, Su Jin | - |
dc.contributor.googleauthor | Lee, Duk Joo | - |
dc.contributor.googleauthor | Baek, Kyung Kee | - |
dc.contributor.googleauthor | Kim, Won-Seog | - |
dc.contributor.googleauthor | Park, Joon Oh | - |
dc.relation.code | 2011207261 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | jieunuhm | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.