WHO Classification of Malignant Lymphomas in Korea: Report of the Third Nationwide Study
- Title
- WHO Classification of Malignant Lymphomas in Korea: Report of the Third Nationwide Study
- Author
- 오영하
- Keywords
- Korea; WHO; Malignant; Lymphoma
- Issue Date
- 2011-06
- Publisher
- The Korean Journal of Pathology 2011, P.45(3), P.254-260
- Citation
- The Korean Journal of Pathology 2011, P.45(3), P.254-260
- Abstract
- Background: The aim of study was to determine the relative frequency of malignant lymphoma according to World Health Organization (WHO) classification in Korea. Methods: A total of 3,998 cases diagnosed at 31 institutes between 2005 and 2006 were enrolled. Information including age, gender, pathologic diagnosis, site of involvement and immunophenotypes were obtained. Results: The relative frequency of non-Hodgkin lymphoma (NHL) and Hodgkin lymphoma (HL) was 95.4% and 4.6%, respectively. B-cell lymphomas accounted for 77.6% of all NHL, while T/natural killer (T/NK)-cell lymphomas accounted for 22.4%. The most frequent subtypes of NHL were diffuse large B-cell lymphoma (42.7%), extranodal marginal zone B-cell lymphoma (MZBCL) of mucosa-associated lymphoid tissue (19.0%), NK/T-cell lymphoma (6.3%) and peripheral T-cell lymphoma (PTCL), unspecified (6.3%), in decreasing order. The relative frequency of HL was nodular sclerosis (47.4%), mixed cellularity (30.6%), and nodular lymphocyte predominant (12.1%) subtypes. Compared with a previous study in 1998, increase in gastric MZBCL and nodular sclerosis HL, and slight decrease of follicular lymphoma, PTCL, and NK/T-cell lymphoma were observed. Conclusions: Korea had lower rates of HL and follicular lymphoma, and higher rates of extranodal NHL, extranodal MZBCL, and NK/T-cell lymphoma of nasal type compared with Western countries. Changes in the relative frequency of lymphoma subtypes are likely ascribed to refined diagnostic criteria and a change in national health care policy.
- URI
- https://www.jpatholtm.org/journal/view.php?doi=10.4132/KoreanJPathol.2011.45.3.254
- ISSN
- 0379-1149
- DOI
- 10.4132/KoreanJPathol.2011.45.3.254
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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