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Electrochemical albumin sensing based on silicon nanowires modified by gold nanoparticles

Title
Electrochemical albumin sensing based on silicon nanowires modified by gold nanoparticles
Author
김영호
Keywords
Amperometric; Silicon nanowire; Gold nanoparticle; Albumin
Issue Date
2011-03
Publisher
ELSEVIER SCIENCE BV
Citation
APPLIED SURFACE SCIENCE, v. 257, NO 10, Page. 4650-4654
Abstract
Si nanowires (SiNWs) were modified by Au nanoparticles (AuNPs) using a self-assembled monolayer of aminopropyltriethoxysilane (APTES) and used for direct sensing of the bovine serum albumin (BSA). It was shown that repeated thermal treatment of the sensor greatly enhanced the reliability of the SiNW sensor by increasing the electrical conductivity largely from carbonization of the APTES molecules and from bringing the AuNPs in intimate contact with the SiNW surface. The AuNP-modified SiNW array sensor was able to detect 1-7 mu M of BSA. The sensor exhibited a good sensitivity over the tested concentration range and linear behavior. It is expected that the proposed label-free biosensor can be further developed to selectively detect and quantify biomolecules other than BSA. (C) 2010 Elsevier B.V. All rights reserved.
URI
http://www.sciencedirect.com/science/article/pii/S0169433210018532?via%3Dihub
ISSN
0169-4332
DOI
10.1016/j.apsusc.2010.12.109
Appears in Collections:
COLLEGE OF ENGINEERING[S](공과대학) > MATERIALS SCIENCE AND ENGINEERING(신소재공학부) > Articles
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