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dc.contributor.author박해영-
dc.date.accessioned2018-02-02T08:11:24Z-
dc.date.available2018-02-02T08:11:24Z-
dc.date.issued2011-04-
dc.identifier.citationFERTILITY AND STERILITY, v. 95, NO 8, Page. 2725-2728en_US
dc.identifier.issn0015-0282-
dc.identifier.urihttp://www.sciencedirect.com/science/article/pii/S001502821100656X?_rdoc=1&_fmt=high&_origin=gateway&_docanchor=&md5=b8429449ccfc9c30159a5f9aeaa92ffb-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/35088-
dc.description.abstractThe her2 messenger RNA (mRNA) was the most abundant among the erb type-1 tyrosine kinase receptors mRNA in human testis and was statistically significantly decreased in impaired spermatogenesis. Testicular HER2 was tyrosine phosphorylated and strongly expressed in spermatogonia, early spermatocytes, elongating/elongated spermatids, Sertoli cells, Leydig cells, and peritubular cells, suggesting that activated HER2 participates in mitosis and meiotic entry of germ cells, spermiogenesis, and steroidogenesis via mediating the epidermal growth factor-growth factor signaling. (Fertil Steril (R) 2011;95:2725-8. (C)2011 by American Society for Reproductive Medicine.)en_US
dc.description.sponsorshipSupported by Hanyang University.en_US
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE INCen_US
dc.subjectGerm cellsen_US
dc.subjectHER2en_US
dc.subjecthumanen_US
dc.subjectsomaen_US
dc.subjecttestisen_US
dc.subjecttyrosine phosphorylateden_US
dc.titleExpression of activated HER2 in human testesen_US
dc.typeArticleen_US
dc.relation.no8-
dc.relation.volume95-
dc.identifier.doi10.1016/j.fertnstert.2011.04.043-
dc.relation.page2725-2728-
dc.relation.journalFERTILITY AND STERILITY-
dc.contributor.googleauthorShin, I-
dc.contributor.googleauthorKim, HJ-
dc.contributor.googleauthorNah, WH-
dc.contributor.googleauthorPark, HJ-
dc.contributor.googleauthorGye, MC-
dc.contributor.googleauthorPark, HY-
dc.relation.code2011203189-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidnopcme-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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