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피부 전이를 보인 목척수의 조직구육종

Title
피부 전이를 보인 목척수의 조직구육종
Other Titles
Case Report : Histiocytic Sarcoma of the Cervical Spinal Cord with Secondary Involvement of the Skin
Author
김정수
Keywords
Histiocytic sarcoma; True histiocytic lymphoma; Malignant histiocytosis
Issue Date
2016-03
Publisher
대한피부과학회
Citation
대한피부과학회지, v. 54, NO 3, Page. 199-202
Abstract
Histiocytic sarcoma is a rare, lymphohematopoietic malignant tumor comprised of tumor cells with the morphological and immunophenotypic features of mature histiocytes. A 35-year-old man presented with a disseminated histiocytic sarcoma that first occurred in the spinal cord and metastasized to the skin and lymph nodes. The tumor cells of the primary histiocytic sarcoma of the spinal cord were very large epithelioid cells with abundant eosinophilic cytoplasms and large, round-to-oval nuclei. In contrast, the metastatic histiocytic sarcoma of the skin was composed of relatively small polygonal cells with well-defined cell borders and high N/C (nucleus/cytoplasm) ratios. Immunohistochemically, both tumors were diffusely positive for histiocyte-associated antigens; but negative for epithelial, melanocyte, lymphoid, and dendritic cell antigens. It is important to recognize the morphological features and immunohistochemical characteristics of metastatic cells in order to ensure accurate diagnoses.
URI
http://kiss.kstudy.com/thesis/thesis-view.asp?key=3421894http://hdl.handle.net/20.500.11754/34266
ISSN
0494-4739
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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