129 0

The beneficial effects of Tai Chi exercise on endothelial function and arterial stiffness in elderly women with rheumatoid arthritis

Title
The beneficial effects of Tai Chi exercise on endothelial function and arterial stiffness in elderly women with rheumatoid arthritis
Author
최보율
Keywords
Rheumatoid arthritis; Tai Chi; Cardiovascular risk
Issue Date
2015-12
Publisher
BIOMED CENTRAL LTD
Citation
ARTHRITIS RESEARCH & THERAPY, v. 17, Article number 380, Page. 1-2
Abstract
Background: Rheumatoid arthritis (RA) has been known to be associated with increased risk of cardiovascular disease (CVD). The aim of this study was to investigate the effects of Tai Chi exercise on CVD risk in elderly women with RA. Method: In total, 56 female patients with RA were assigned to either a Tai Chi exercise group (29 patients) receiving a 3-month exercise intervention once a week or a control group (27 patients) receiving general information about the benefits of exercise. All participants were assessed at baseline and at 3 months for RA disease activity (Disease Activity Score 28 and Routine Assessment of Patient Index Data 3), functional disability (Health Assessment Questionnaire), CVD risk factors (blood pressure, lipids profile, body composition, and smoking), and three atherosclerotic measurements: carotid intima-media thickness, flow-mediated dilatation (FMD), and brachial-ankle pulse wave velocity (baPWV). Results: FMD, representative of endothelial function, significantly increased in the Tai Chi exercise group (initial 5.85 +/- 2.05 versus 3 months 7.75 +/- 2.53 %) compared with the control group (initial 6.31 +/- 2.12 versus 3 months 5.78 +/- 2.13 %) (P = 1.76 x 10(-3)). Moreover, baPWV, representative of arterial stiffness, significantly decreased in the Tai Chi exercise group (initial 1693.7 +/- 348.3 versus 3 months 1600.1 +/- 291.0 cm/s) compared with the control group (initial 1740.3 +/- 185.3 versus 3 months 1792.8 +/- 326.1 cm/s) (P = 1.57 x 10(-2)). In addition, total cholesterol decreased significantly in the Tai Chi exercise group compared with the control group (-7.8 +/- 15.5 versus 2.9 +/- 12.2 mg/dl, P = 2.72 x 10(-2)); other changes in RA-related characteristics were not significantly different between the two groups. Tai Chi exercise remained significantly associated with improved endothelial function (FMD; P = 4.32 x 10(-3)) and arterial stiffness (baPWV; P = 2.22 x 10(-2)) after adjustment for improvement in total cholesterol level. Conclusion: Tai Chi exercise improved endothelial dysfunction and arterial stiffness in elderly women with RA, suggesting that it can be a useful behavioral strategy for CVD prevention in patients with RA.
URI
https://arthritis-research.biomedcentral.com/articles/10.1186/s13075-015-0893-xhttp://hdl.handle.net/20.500.11754/29452
ISSN
1478-6354; 1478-6362
DOI
10.1186/s13075-015-0893-x
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE