Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 배상철 | - |
dc.date.accessioned | 2016-05-26T05:11:11Z | - |
dc.date.available | 2016-05-26T05:11:11Z | - |
dc.date.issued | 2015-01 | - |
dc.identifier.citation | CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, v. 33, NO 2, Page. 166-173 | en_US |
dc.identifier.issn | 1593-098X | - |
dc.identifier.uri | http://www.clinexprheumatol.org/abstract.asp?a=8351 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/21361 | - |
dc.description.abstract | Objective The purpose of this study was to compare the diagnostic performance of procalcitonin and C-reactive protein (CRP) for bacterial infection in patients with systemic rheumatic diseases. Methods We searched Medline, Embase, and the Cochran library, and performed two meta-analyses on the diagnostic accuracy of procalcitonin and CRP for bacterial infection in systemic rheumatic disease patients. Results A total of eight studies including 668 patients in whom the patients with bacterial infection were 208 were available for the meta-analysis. The pooled sensitivity and specificity of procalcitonin were 66.8% (95% confidence interval [CI] 60.0-73.2) and 89.8% (86.6-92.4), respectively, and those of CRP were 81.3% (75.3-86.3) and 63.0% (58.5-67.5). Procalcitonin PLR, NLR, and DOR were 5.930 (3.593-9.786), 0.352 (0.229-0.539), and 19.33 (10.25-36.45), respectively, and those for CRP were 2.228 (1.376-3.608), 0.367(0.252-0.534), and 7.066 (3.559-14.03), respectively. The AUC of procalcitonin was 0.884 and the Q* index was 0.814, while the AUC of CRP was 0.789 and the Q index was 0.726, which indicated that the diagnostic accuracy of procakitonin in patients with systemic rheumatic diseases is higher than that of CRP (difference of AUC 0.095, 95% CI 0.004-0.185, p=0.039). When the data were limited to SLE, the specificity of procalcitonin was also significantly higher than that of CRP (difference 0.219, 95% CI 0.127-0.310, p˂0.0001). Conclusion Our meta-analysis of published studies demonstrates that procalcitonin is more specific and has better diagnostic accuracy than CRP for bacterial infection in systemic rheumatic diseases. | en_US |
dc.language.iso | en | en_US |
dc.publisher | CLINICAL & EXPER RHEUMATOLOGY | en_US |
dc.subject | Bacterial infection | en_US |
dc.subject | CRP | en_US |
dc.subject | Diagnostic accuracy | en_US |
dc.subject | Meta-analysis | en_US |
dc.subject | Procalcitonin | en_US |
dc.subject | Rheumatic diseases | en_US |
dc.title | Diagnostic accuracies of procalcitonin and C-reactive protein for bacterial infection in patients with systemic rheumatic diseases: a meta-analysis | en_US |
dc.type | Article | en_US |
dc.relation.no | 2 | - |
dc.relation.volume | 33 | - |
dc.relation.page | 166-173 | - |
dc.relation.journal | CLINICAL AND EXPERIMENTAL RHEUMATOLOGY | - |
dc.contributor.googleauthor | Song, G. G. | - |
dc.contributor.googleauthor | Bae, S. C. | - |
dc.contributor.googleauthor | Lee, Y. H. | - |
dc.relation.code | 2015001627 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | scbae | - |
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