Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 김동립 | - |
dc.date.accessioned | 2022-11-24T02:10:37Z | - |
dc.date.available | 2022-11-24T02:10:37Z | - |
dc.date.issued | 2021-06 | - |
dc.identifier.citation | Nature Communications, v. 12, NO. 1, article no. 3710 | en_US |
dc.identifier.issn | 2041-1723 | en_US |
dc.identifier.uri | https://www.nature.com/articles/s41467-021-23959-3 | en_US |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/177355 | - |
dc.description.abstract | The growing need for the implementation of stretchable biosensors in the body has driven rapid prototyping schemes through the direct ink writing of multidimensional functional architectures. Recent approaches employ biocompatible inks that are dispensable through an automated nozzle injection system. However, their application in medical practices remains challenged in reliable recording due to their viscoelastic nature that yields mechanical and electrical hysteresis under periodic large strains. Herein, we report sponge-like poroelastic silicone composites adaptable for high-precision direct writing of custom-designed stretchable biosensors, which are soft and insensitive to strains. Their unique structural properties yield a robust coupling to living tissues, enabling high-fidelity recording of spatiotemporal electrophysiological activity and real-time ultrasound imaging for visual feedback. In vivo evaluations of custom-fit biosensors in a murine acute myocardial infarction model demonstrate a potential clinical utility in the simultaneous intraoperative recording and imaging on the epicardium, which may guide definitive surgical treatments. © 2021, The Author(s). | en_US |
dc.description.sponsorship | We thank Bill Schoenlein and Melissa Bible for their help with the porcine surgeries. C.H.L. acknowledges funding supports from the Asian Office of Aerospace Research & Development (AOARD: FA2386-16-1-4105; program manager: Dr. Tony Kim) and the Air Force Office of Scientific Research (AFOSR: FA2386-18-1-40171; program manager: Dr. Tony Kim). C.H.L. also acknowledges funding supports from the SMART film by the Birck Nanotechnology Center at Purdue University. K.-S.L. acknowledges support from the US Department of Energy’s National Nuclear Security Administration contract DE-AC52-06NA25396 and the Dynamic Materials Properties Campaign. The Los Alamos National Laboratory is an affirmative action equal opportunity employer, managed by Triad National Security, LLC for the U.S. Department of Energy’s NNSA, under contract 89233218CNA000001. H.L. acknowledges funding support from the National Science Foundation (United States) under grants ECCS-1944480 and CNS-1726865. C.H.P. acknowledges funding support from the National Research Foundation of Korea (NRF) Grant funded by the Korea government (MSIT) (NRF-2017R1C1B3009270 and 2019R1A2C1087209). D.R.K. acknowledges funding support from the International Research and Development Program (NRF-2018K1A3A1A32055469) and the Basic Science Research Program (NRF-2018R1C1B6007938) through the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT of Korea. D.R.K acknowledges funding support from the International Research and Development Program (NRF- 2018K1A3A1A32055469) through the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT of Korea. H.J. acknowledges the funding support from the MOTIE (Ministry of Trade, Industry, and Energy) in Korea under the Fostering Global Talents for Innovative Growth Program (P0008748, Global Human Resource Development for Innovative Design in Robot and Engineering) supervised by the Korea Institute for Advancement of Technology (KIAT). Additional funding was provided by the Leslie A. Geddes Endowment at Purdue University (C.H.L. and C.J.G.). | en_US |
dc.language | en | en_US |
dc.publisher | Nature Research | en_US |
dc.source | 80795_김동립.pdf | - |
dc.title | Rapid custom prototyping of soft poroelastic biosensor for simultaneous epicardial recording and imaging | en_US |
dc.type | Article | en_US |
dc.relation.no | 1 | - |
dc.relation.volume | 12 | - |
dc.identifier.doi | 10.1038/s41467-021-23959-3 | en_US |
dc.relation.journal | Nature Communications | - |
dc.contributor.googleauthor | Kim, Bongjoong | - |
dc.contributor.googleauthor | Soepriatna, Arvin H. | - |
dc.contributor.googleauthor | Park, Woohyun | - |
dc.contributor.googleauthor | Moon, Haesoo | - |
dc.contributor.googleauthor | Cox, Abigail | - |
dc.contributor.googleauthor | Zhao, Jianchao | - |
dc.contributor.googleauthor | Gupta, Nevin S. | - |
dc.contributor.googleauthor | Park, Chi Hoon | - |
dc.contributor.googleauthor | Kim, Kyunghun | - |
dc.contributor.googleauthor | Jeon, Yale | - |
dc.contributor.googleauthor | Jang, Hanmin | - |
dc.contributor.googleauthor | Kim, Dong Rip | - |
dc.contributor.googleauthor | Lee, Hyowon | - |
dc.contributor.googleauthor | Lee, Kwan-Soo | - |
dc.contributor.googleauthor | Goergen, Craig J. | - |
dc.contributor.googleauthor | Lee, Chi Hwan | - |
dc.sector.campus | S | - |
dc.sector.daehak | 공과대학 | - |
dc.sector.department | 기계공학부 | - |
dc.identifier.pid | dongrip | - |
dc.identifier.orcid | https://orcid.org/0000-0001-6398-9483 | - |
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